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metabolized in the liver

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13y ago

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Why might choledocolithiasis cause jaundice?

well, you see.. jaundice is caused by the elevation of UNCONJUGATED bilirubin level in our blood.. a high level of unconjugated bilirubin in blood will enter our body tissue and make our skin looks yellow.bilirubin is metabolized in the liver, thus making the unconjugated bilirubin changed into conjugated one. and these conjugated bilirubin will be excreted to our intestine and it will give color to our urine an feces.in patients with choledocolithiasis, there is an obstruction caused by the gallstone inside the duct where conjugated bilirubin should be excreted.. this obstruction makes the liver unable to metabolize the unconjugated bilirubin, and so the level of unconjugated bilirubin will rise, having effect of jaundice.


What is the relationship between rapid rate of RBC destruction and jaundice?

When red blood cells are broken down rapidly, the heme component of hemoglobin is metabolized into bilirubin. If the rate of breakdown exceeds the liver's ability to process bilirubin, it can accumulate in the blood and tissues, leading to jaundice, a yellowing of the skin and eyes. This is seen in conditions such as hemolytic anemia or certain liver diseases.


What converts hemoglobin into bile?

Hemoglobin is broken down into biliverdin by macrophages in the spleen. Biliverdin is then converted into bilirubin, which is further metabolized into bile in the liver. Bile is important for the digestion and absorption of fats in the small intestine.


What are the pigments released by the liver in bile called?

From the glossary of medical terms the answer is: BILIRUBIN


What is the color of bilirubin?

The color of Bilirubin is orange Bilirubin is an orange color pigment in the bile


What the types of serum bilirubin?

Serum bilirubin is primarily categorized into three types: direct (conjugated) bilirubin, indirect (unconjugated) bilirubin, and total bilirubin. Direct bilirubin is water-soluble and occurs after the liver processes bilirubin, while indirect bilirubin is fat-soluble and represents bilirubin that has not yet been conjugated by the liver. Total bilirubin is the sum of both direct and indirect bilirubin levels in the blood, often measured to assess liver function and diagnose various medical conditions.


What is another name for bile pigment?

Bilirubin


End product of hemoglobin breakdown is?

bilirubin


Pigment produced by the destruction of hemoglobin in the liver is called?

When the erythrocytes are destroyed, haemoglobin breaks down, the heme part of it goes through a series of transformation: Heme → biliverdin (green pigment) biliverdin → bilirubin (orange-yellow pigment) Bilirubin + blood albumin → bound bilirubin (in peripheral blood) Bound bilirubin + glucuronic acid → conjugated bilirubin. (in liver) Conjugated bilirubin + intestinal bacteria → several pigments, including - stercobolin (orange-brown pigment, excreted in feces) and - urobilinogen (reabsorbed into bile/blood, finally excreted in urine)


Can indirect bilirubin be more than total bilirubin?

yes


Is raised bilirubin a sign or a symptom?

Raised bilirubin is a symptom


Total and fractionated bilirubin?

Liver makes bilirubin water soluble for excretion into the urine....get total bilirubin from complete CFP...