metabolized in the liver
well, you see.. jaundice is caused by the elevation of UNCONJUGATED bilirubin level in our blood.. a high level of unconjugated bilirubin in blood will enter our body tissue and make our skin looks yellow.bilirubin is metabolized in the liver, thus making the unconjugated bilirubin changed into conjugated one. and these conjugated bilirubin will be excreted to our intestine and it will give color to our urine an feces.in patients with choledocolithiasis, there is an obstruction caused by the gallstone inside the duct where conjugated bilirubin should be excreted.. this obstruction makes the liver unable to metabolize the unconjugated bilirubin, and so the level of unconjugated bilirubin will rise, having effect of jaundice.
When red blood cells are broken down rapidly, the heme component of hemoglobin is metabolized into bilirubin. If the rate of breakdown exceeds the liver's ability to process bilirubin, it can accumulate in the blood and tissues, leading to jaundice, a yellowing of the skin and eyes. This is seen in conditions such as hemolytic anemia or certain liver diseases.
From the glossary of medical terms the answer is: BILIRUBIN
The color of Bilirubin is orange Bilirubin is an orange color pigment in the bile
Hemoglobin is broken down into biliverdin by macrophages in the spleen. Biliverdin is then converted into bilirubin, which is further metabolized into bile in the liver. Bile is important for the digestion and absorption of fats in the small intestine.
Bilirubin
bilirubin
When the erythrocytes are destroyed, haemoglobin breaks down, the heme part of it goes through a series of transformation: Heme → biliverdin (green pigment) biliverdin → bilirubin (orange-yellow pigment) Bilirubin + blood albumin → bound bilirubin (in peripheral blood) Bound bilirubin + glucuronic acid → conjugated bilirubin. (in liver) Conjugated bilirubin + intestinal bacteria → several pigments, including - stercobolin (orange-brown pigment, excreted in feces) and - urobilinogen (reabsorbed into bile/blood, finally excreted in urine)
yes
Raised bilirubin is a symptom
Liver makes bilirubin water soluble for excretion into the urine....get total bilirubin from complete CFP...
The presence of bilirubin can be confirmed through blood tests such as a total bilirubin test or a direct bilirubin test. These tests measure levels of bilirubin in the blood to assess liver function and diagnose conditions such as jaundice or liver disease.