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The greatest loss of life in a single event occurred during World War II, particularly in the Holocaust, where approximately six million Jews were systematically murdered by the Nazi regime. Another significant event was the atomic bombings of Hiroshima and Nagasaki in 1945, which resulted in hundreds of thousands of casualties. Additionally, natural disasters like the 1931 China floods also led to millions of deaths, highlighting the devastating impact of both human actions and natural phenomena on human life.

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