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Let's start with the first phrase:

"All immunogens are antigens"

Yes, that's true. Immunogens are antigens that CAN ELICIT IMMUNE RESPONSE and percieved as foreign by the body. Remember, anything that is percieved by the body as foreign is an antigen. Period.

Now the second phrase:

"All antigens are not immunogens"

This is also true. There are antigens, percieved by the body as foreign that CANNOT ELICIT IMMUNE RESPONSE. Example of this is Hapten Molecule. It is an antigen that cannot elicit response by itself, unless paired with a larger protein.

In summary:

Immunogens - form of antigens that can elicit response.

Antigens - anything percieved by the body as foreign that can either elicit or not (Hapten molecule) an Immune response.

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12y ago

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Differences between immunogen and antigen?

An Antigen is considered as any foreign particle that enters the body such as dust, food and any microorganisms. An Immunogen is any foreign particle that triggers an response from the body's immune system. Consequently, all Immunogens are Antigens, but not all Antigens are Immunogens. To be considered an Immunogen, the particle has to have all the following characteristics: 1- Has enough atomic mass to be recognized by T cells and Antigen Presenting cells 2- Be significantly different from all of our cells or metabolites. 3- Must have a defined secondary and tertiary structure (has to be firm to form an epitope) 4- Has to be an antigen eg: Carbohydrates are not a highly immunogenic antigen, since they are made of glucose which is essential for our body's metabolism. Moreover, our body has the ability to store glucose as glycogen. An Adjuvant is a compound that increases the immunogenicy of antigens when mixed together.


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