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The mutation in the gene alters the amino acid sequence of the resulting protein, potentially impacting its structure and function. This change can lead to a loss of activity, gain of a new function, or altered stability of the protein. Depending on the nature of the mutation, the protein may be less effective in its normal role or may interact differently with other cellular components. Ultimately, these changes can have significant effects on cellular processes and may contribute to disease.
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What is one or two nucleotides that are changed in a certain mutation?
In a point mutation, a change in a single nucleotide can lead to a specific mutation. For example, a substitution mutation occurs when one nucleotide is swapped for another, such as A to T or C to G. This change can result in different amino acids being coded for in the protein sequence.
How can a point mutation alter the final structure of a protein?
In a point mutation, one nitrogen base is substituted for the correct base. Since most amino acids can be coded for by more than one codon, there may be no consequence to this mutation. However, sometimes a point mutation results in an incorrect amino acid being added to the amino acid sequence of the protein. This can cause a change in the shape and therefore function of the protein, which can be a harmful mutation. Two genetic disorders caused by a point mutation are cystic fibrosis and sickle cell anemia.
If a strand of DNA with the sequence TGA mutated to GCA would it be a silent or missense mutation?
Both a silent and missense mutation is a change in one nucleotide. However, a silent mutation still codes for the same amino acid, but a missense mutation codes for a different amino acid. This means that a silent mutation will have no affect on the resulting protein, but a missense mutation will. Still, it is not guaranteed that a a missense mutation will result in a disfunction of created protein, as long as it is not occurring in the activation site.
Will the protein coded by the mutated strand of DNA function differently from the original strand?
It depends on the particular mutation. Some are "silent" which means the substitution of a base actually codes for the same amino acid as the previous. In this case, the sequence and function of the polypeptide is exactly the same. If the mutation is a nonsense or missense mutation however, then the structure and function of the protein is indeed affected. A nonsense mutation results in a codon becoming a "stop" codon, thereby terminating the polypeptide prematurely. Such proteins are nonfunctional. Missense mutations result in the change in sequence of amino acids; one amino acid takes the place of another due to the changed codon. These proteins can also be non-functional, but sometimes they can function, albeit less efficiently.
What protein is produced when gene is activated through transcription and translation?
The protein coded for in the DNA transcribed ad then translated.
What happens if only one amino acid is coded incorrectly?
If only one amino acid is coded incorrectly in a protein sequence, it may result in a missense mutation. This could potentially lead to a change in the structure and function of the protein. The impact of the mutation would depend on the specific amino acid involved and its location within the protein.
What is one or two nucleotides that are changed in a certain mutation?
In a point mutation, a change in a single nucleotide can lead to a specific mutation. For example, a substitution mutation occurs when one nucleotide is swapped for another, such as A to T or C to G. This change can result in different amino acids being coded for in the protein sequence.
What happens in a substitution mutation and how does it impact the genetic code?
In a substitution mutation, a single nucleotide in the DNA sequence is replaced with a different nucleotide. This can change the amino acid that is coded for, potentially altering the protein that is produced. This can lead to changes in the genetic code, which may result in a different protein being produced or a non-functional protein.
What amino acid is coded for by this sequences after mutation?
hahaqhaq
What happens during a substitution mutation and how does it impact the genetic code?
During a substitution mutation, a single nucleotide in the DNA sequence is replaced with a different nucleotide. This can lead to a change in the amino acid that is coded for, potentially altering the protein that is produced. The impact on the genetic code depends on whether the substitution results in a silent mutation (no change in the amino acid) or a missense mutation (change in the amino acid), which can affect the function of the protein.
What amino acid is coded for by this sequence before mutation?
The neutral mutation does not change the amino acid coded for by the codon. A good example is the RNA codon that could be the CCA, CCC or the CCG.
How can a point mutation alter the final structure of a protein?
In a point mutation, one nitrogen base is substituted for the correct base. Since most amino acids can be coded for by more than one codon, there may be no consequence to this mutation. However, sometimes a point mutation results in an incorrect amino acid being added to the amino acid sequence of the protein. This can cause a change in the shape and therefore function of the protein, which can be a harmful mutation. Two genetic disorders caused by a point mutation are cystic fibrosis and sickle cell anemia.
How does a mutation change a codon for one amino acid into a different codon for the same amino acid?
A mutation can change a codon for one amino acid into a different codon for the same amino acid through a process called silent mutation. This type of mutation occurs when a change in the DNA sequence does not alter the amino acid that is coded for, resulting in the same protein being produced.
If a strand of DNA with the sequence TGA mutated to GCA would it be a silent or missense mutation?
Both a silent and missense mutation is a change in one nucleotide. However, a silent mutation still codes for the same amino acid, but a missense mutation codes for a different amino acid. This means that a silent mutation will have no affect on the resulting protein, but a missense mutation will. Still, it is not guaranteed that a a missense mutation will result in a disfunction of created protein, as long as it is not occurring in the activation site.
When geneticists speak of mutation they are referring to?
In genetics, mutation refers to a change in the sequence of genes. This can mean a change in the genes in an organism's DNA or in the DNA/RNA of a virus. There are many different types of mutations, which will have differing effects depending on how many bases/sections have been changed, where the sections are located and how different the resultant protein(s) will be. For example; a change in one base, that does not change the amino acid that will be coded for is called a silent mutation. This will have no affect on the resulting protein or the organism.
What happens to a strand of DNA when there is a change in the base on the other strand?
This is called a "mutation." What ends up happening depends on where the base that changed was located. If the changed base is on the side of the DNA strand that is not used in making mRNA, there will be no difference in the final protein made whatsoever. If the mutation occurs in a part of the DNA that is not coded to make a protein (so called "junk" DNA), there will also be no change in the final protein, because there won't be a protein made. Even if the mutation occurs in a segment of DNA that eventually makes a protein, if the replacement base causes the mRNA to code for an amino acid that is similar to the original base, there will be little change. There is more to it, but that will probably suffice.
How could a mutation be helpful rather than harmful?
a bad mutation would be if your DNA coded for you not to be able to digest fats. you would starve to death.
