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Point mutations will only affect a aingle amino acid in a protein chain, which could or could not affect the actual protein. If a point mutation occured and coded for a stop codon, that would be an example of one way it could affect the protein chain. However, since there are 20 different amino acids but 64 different ways to form codon combinations, 4 nucleotides and 3 slots in a codon 4^3=64, some different codons code for the same end amino acid.

Frameshifts, however, affect every single codon after the shift occurs. This will occurs when an extra nucleotide is added, or one is removed from the mRNA which is responsible for directing which amino acids go where on a protein chain. Look how the meaning of the sentence changes with the frame shift.

|___| represent codons

letters represent nucleotides

the | cat | ate | the | rat

^--- Correct Sequence

the | aca | tat | eth | era | t

^--- Sequence with an extra 'a' before 'cat'

Notice how the frames of all the words after cat are changed. This can occur with a missing or extra nucleotide.

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Related Questions

How could a mutation affect the process of translation?

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What mutation stops translation of the mRNA?

The type of mutation that stops the translation of a protein is a nonsense mutation. This occurs when a base substitution (point mutation) results in a STOP codon and thus stops translation of the sequence into a protein.


What is a non polar mutation?

a mutation in a gene that does not affect the downstream genes in an operon. ie. a polar mutation is one that DOES affect the transcription or translation of genes in the same operon downstream of your gene of interest.


How a mutation may not affect an organisms traits?

A mutation does not affect an organism trait for a reason. It is neutral which depends on the environment.


Why does an insertion mutation usually cause more defects in protein synthesis than a point mutation?

Insertion mutations can affect many amino acids in the protein.An insertion mutation usually causes more defects during protein synthesis than point mutation because an insertion mutation will affect many amino acids in the protein.


What mutation most likely can affect a cow offspring?

A mutation in egg cells


How mutation can affect a gene?

it changes it


What type of mutation will affect the largest number of proteins produces by an organism?

Chromosomal mutation


Which mutation cannot occur in a tRNA encoding gene?

A mutation that changes the start codon of a tRNA gene is unlikely to occur, as that could prevent proper translation of the tRNA. Mutations that disrupt critical structural elements such as the anticodon loop or the acceptor stem are also less likely, as they would affect the tRNA's functionality.


What is an example of a good effect from a mutation?

Well a Silent Mutation does not affect anything so it isn't bad so its a good mutation.


How does a mutation in a cell affect an organism?

A mutation in a sex cell means that the mutation can be passed on to the individuals offspring. If the mutation just occurred in a somatic cell, it would not be passed down.


How does a mutation in a sex differ from a from a mutation in a non-sex cell?

A mutation in a sex cell, such as a sperm or egg cell, can be passed on to offspring and affect future generations. In contrast, a mutation in a non-sex cell will only affect the individual and is not passed on to offspring.