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This can't be answered simply. Are we talking about prokaryotic or eukaryotic genes? If eukaryotic, there are a whole bunch of non-coding sequences that make up said gene that do not make it into the final translated product, but are required for the gene to get out of the nucleus and be translated into protein.

I think the smallest gene recorded so far apparently encodes a 7amino acid protein - so the coding sequence alone for that gene would be 24 aa's (3 per each amino acid + 3 for the start codon, ATG). In my own graduate research, I have worked with genes that are over 25kb, that is, 25000 nucleotides long. There are certainly genes that are much larger than that, as well.

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