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Answering this question is impossible since the quantity "mole" is always related to some chemical substance.

One mole of a substance is defined as about 6.022 * 10^23 units of this substance. For example one mole of H2O consists of 6.022 * 10^23 molecules of H2O. On mole of beer bottles is made up by 6.022 * 10^23 bottles of beer. Obviously one mole of beer bottles is a bit heavier then on mole of water.

The exact mass of a mole of a substance is derived from its molecular weight. the factor of 6.022 * 10^23 (the Avogadro-number) converts the Atomic Mass to the mass in grams.

One molecule of CaCO3 has the atomic mass of (40 + 12 + 3 * 16) u = 100 u.
Thus one mole of CaCO3 has the mass of 100 g.

4.26 g for instance equal to 2.113 moles of H2 (having an molecular weight of 2.016 u).

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