Chromosomes fails to split during mitosis. That is non-dis junction. Due to that, different proteins are produced. (because the DNA is messed up and so is the amino acid chain. That is why different protein is produced that needed.) That causes serious problems. Not all mutations are harmful.
Nondisjunction is an error in cell division that can lead to an abnormal number of chromosomes in a cell. When nondisjunction occurs in germ cells, it can be inherited by offspring, leading to genetic disorders such as Down syndrome. The risk of inheriting nondisjunction increases with parental age.
Nondisjunction occurs during the Anaphase stage of Meiosis. In this stage, the sister chromosomes move to opposite sides of the cell. However, in Nondisjunction one or more set(S) of chromosomes move to the same side of the cell.
The three types of nondisjunction are autosomal nondisjunction, sex chromosome nondisjunction, and structural chromosome nondisjunction. Autosomal nondisjunction involves the failure of homologous chromosomes to separate during cell division. Sex chromosome nondisjunction involves the failure of sex chromosomes to separate. Structural chromosome nondisjunction involves the incorrect separation of chromosome parts during cell division.
Nondisjunction occurs during anaphase, usually when referring to meiosis, when a tetrad fails to separate.
Nondisjunction is the failure of a homolog to separate during meiosis causing trisomy (an extra chromosome) or monosomy (a missing chromosome), it can be harmful because it is a mutation that can cause many devastating disease, for example nondisjunction of the 21st chromosome causes down syndrome, another example of nondisjunction being harmful, is nondisjunction of the sex chromosomes, causing Turner's or Klinefelter's syndrome two very devastating diseases.
What occurs during nondisjunction
If nondisjunction occurs during meiosis the result could be a wide range of mutations. Most likely it would result in mosaicism meaning there will be a mixture of affected cells and non affected cells.
Nondisjunction
Nondisjunction is an error in cell division that can lead to an abnormal number of chromosomes in a cell. When nondisjunction occurs in germ cells, it can be inherited by offspring, leading to genetic disorders such as Down syndrome. The risk of inheriting nondisjunction increases with parental age.
If nondisjunction occurs during meiosis, it results in the improper separation of chromosomes, leading to gametes with an abnormal number of chromosomes. When these gametes fuse during fertilization, the resulting zygote may have an extra chromosome (trisomy) or a missing chromosome (monosomy). This can lead to genetic disorders, such as Down syndrome, which is caused by an extra copy of chromosome 21. Nondisjunction can occur in either meiosis I or meiosis II, with differing impacts on the resulting gametes.
Nondisjunction forms and causes Aneoploidy
Nondisjunction occurs during the separation of chromosomes in either meiosis or mitosis, leading to an abnormal number of chromosomes in the resulting cells.
Nondisjunction occurs in too many cells or too few cells causing defects
No, achondroplasia is not caused by nondisjunction. Achondroplasia is a genetic disorder caused by a spontaneous mutation in a gene involved in bone growth. Nondisjunction is a genetic event that occurs during cell division and can lead to abnormal chromosome numbers in offspring.
Down sydrome because of nondisjunction in the chromosomes
Nondisjunction during mitosis can lead to aneuploidy, where cells have an abnormal number of chromosomes, which can result in developmental abnormalities or cell death. If an individual has somatic cells with nondisjunction, it can lead to mosaicism, where different cells in the body have different chromosome numbers, potentially causing genetic disorders or health issues.
It is the failure of chromosome pairs to separate properly during cell division.