The pathogenic DNA from the dead bacteria became active when combined with the DNA in the live bacteria. When injected into the mice, this reactivated DNA caused the disease and the mice died.
The injection resulted in the mice developing pneumonia and dying. This experiment by Griffith in 1928 demonstrated that genetic material could be transferred between bacteria, leading to the concept of bacterial transformation and ultimately the discovery of DNA as the genetic material.
Fred Griffith discovered that the harmless R strain of Streptococcus pneumoniae could be transformed into the deadly S strain when mixed with heat-killed S strain bacteria. This experiment provided evidence for the concept of bacterial transformation, where genetic material can be transferred between different strains of bacteria.
In Griffith's experiment 1 he injected the mouse with live R cells.It was not till Griffiths experiment 2 did he injest the mouse with live S cells.
Assuming you mean the Frederick Griffith bacterial experiment, the question left unanswered was how the rough strain (less harmful) bacteria transformed into the smooth strain (lethal) bacteria. When he injected live rough strain bacteria, the mouse lived. When he injected live smooth strain bacteria, the mouse died. But if dead smooth strain bacteria was injected, the mouse lived. So if either live rough strain or dead smooth strain could be injected without killing the mouse, then it would stand to reason that one could inject both, the mouse should live. But the mouse died. So he figured the rough strain was somehow taking on the characteristics of the smooth strain bacteria, perhaps by being in close proximity to dead smooth strain bacteria, but he didn't know why. We now know that the smooth strain DNA was somehow getting grafted into the rough strain bacteria and making it able to create a coating which prevented the immune system (of the mouse in this case) from killing it. In case you mean the John Howard Griffin racial change experiment, the question left unanswered was how to stop racism. While his experiment was not completely successful, he gained a number of insights into the experiences of men of color in America. He was able to speak to people in both groups, but yet, he was not able at that point to get them to reconcile with each other.
Radioactively tagged bacteriophages are used to confirm that DNA, not protein, is injected into host cells during infection. The radioactively labeled DNA can be detected inside the host cells after infection, providing evidence that DNA is the genetic material transferred by the bacteriophages. This experiment was crucial in establishing DNA as the genetic material in organisms.
The injection resulted in the mice developing pneumonia and dying. This experiment by Griffith in 1928 demonstrated that genetic material could be transferred between bacteria, leading to the concept of bacterial transformation and ultimately the discovery of DNA as the genetic material.
To find out, he took a culture of these cells, heated the bacteria to kill them, and injected the heat-killed bacteria into the mice.
To find out, he took a culture of these cells, heated the bacteria to kill them, and injected the heat-killed bacteria into the mice.
To find out, he took a culture of these cells, heated the bacteria to kill them, and injected the heat-killed bacteria into the mice.
To find out, he took a culture of these cells, heated the bacteria to kill them, and injected the heat-killed bacteria into the mice.
Fred Griffith discovered that the harmless R strain of Streptococcus pneumoniae could be transformed into the deadly S strain when mixed with heat-killed S strain bacteria. This experiment provided evidence for the concept of bacterial transformation, where genetic material can be transferred between different strains of bacteria.
To find out, he took a culture of these cells, heated the bacteria to kill them, and injected the heat-killed bacteria into the mice.
S Strain ---> inject into mice ---> Mice Die R Strain ---> inject into mice ---> Mice Live Griffith was able to kill bacteria by heating them. He observed that heat-killed S Strain bacteria injected into mice did not kill them. When he S Strain (heat Killed) ---> Injected into mice ---> Mice Live S Strain ( heat Killed) + R Strain (Live) ---> Injected into mice ---> Mice Die
To find out, he took a culture of these cells, heated the bacteria to kill them, and injected the heat-killed bacteria into the mice. The Mice survived, suggesting that the cause of pneumonia was not a chemical poison released by the disease-causing bacteria.
In Griffith's experiment 1 he injected the mouse with live R cells.It was not till Griffiths experiment 2 did he injest the mouse with live S cells.
Assuming you mean the Frederick Griffith bacterial experiment, the question left unanswered was how the rough strain (less harmful) bacteria transformed into the smooth strain (lethal) bacteria. When he injected live rough strain bacteria, the mouse lived. When he injected live smooth strain bacteria, the mouse died. But if dead smooth strain bacteria was injected, the mouse lived. So if either live rough strain or dead smooth strain could be injected without killing the mouse, then it would stand to reason that one could inject both, the mouse should live. But the mouse died. So he figured the rough strain was somehow taking on the characteristics of the smooth strain bacteria, perhaps by being in close proximity to dead smooth strain bacteria, but he didn't know why. We now know that the smooth strain DNA was somehow getting grafted into the rough strain bacteria and making it able to create a coating which prevented the immune system (of the mouse in this case) from killing it. In case you mean the John Howard Griffin racial change experiment, the question left unanswered was how to stop racism. While his experiment was not completely successful, he gained a number of insights into the experiences of men of color in America. He was able to speak to people in both groups, but yet, he was not able at that point to get them to reconcile with each other.
Griffith discovered that the mice still died, indicating that the harmless bacteria had been transformed into disease-causing bacteria by a hereditary factor from the heat-killed bacteria. This experiment laid the foundation for the discovery of bacterial transformation by Avery, MacLeod, and McCarty.