This extra chromosome in a gamete occurs as a result of a process called nondisjunction, where chromosomes fail to separate properly during meiosis. As a result, one gamete may end up with an extra chromosome, leading to conditions such as Down syndrome when that gamete contributes to fertilization. Nondisjunction can happen during either the first or second meiotic division and can affect any of the chromosomes.
If nondisjunction occurs in meiosis II for one chromosome, the result would be that one gamete receives an extra copy of the chromosome and one gamete lacks that chromosome. This results in aneuploidy in the offspring, which can lead to genetic disorders such as Down syndrome.
how could a zygote end up with an extra chromosome Either the egg or the sperm doesn't divide equally.
Meiotic nondisjunction. In meiosis I or II, chromosome pair 21 fail to separate correctly, leaving one gamete with an extra chromosome 21.
Trisomy occurs when an individual has three copies of a particular chromosome instead of the usual two. This can happen during the formation of sperm or egg cells, leading to an extra copy of the chromosome in the resulting embryo. Trisomy can result in conditions like Down syndrome, where there is an extra copy of chromosome 21.
Down Syndrom
an error in meiotic cell division
If nondisjunction occurs in meiosis II for one chromosome, the result would be that one gamete receives an extra copy of the chromosome and one gamete lacks that chromosome. This results in aneuploidy in the offspring, which can lead to genetic disorders such as Down syndrome.
It gives one of the gametes an extra chromosome and leaves the other gamete with one less chromosome.
Addition of a pair of chromosomes to a diploid set results in tetrasomic condition. Tetrasomics may be represented as 2N+2. Tetrasomics may arise when two abonormal gametes produced as a result of non-disjuction unite, with each gamete carrying an extra chromosome of the same pair as shown below. AABBCCDD a diploid cell----meiosis and non disjuction AABC Gamete carrying an extra chromosome--- BC Gamete short of one chromosome. Now if this Gamete (AABC) unites with another gamete of the same kind (AABC), we get tetrasomic AAAABBCC.
Down's Syndrome is caused due to the presence of an extra 21st chromosome, resulting in 3 sets of 21st chromosome instead of just 2. This is because during Anaphase II of Meiosis II non-disjunction occurs and instead of one 21st chromosome going into each gamete, both go into one of the gametes and none goes into the other. When a normal gamete fuses with the gamete with an extra21st chromosome, it forms a zygote with 3 sets of 21st chromosome instead of 2 and that is known as Down's Syndrome.
A trisomy. Trisomies are usually fatal in all chromosome pairs except 5, 13, 21 (these cause Down syndrome), and 23 (The chromosome pair that determines gender)
two chromosomall diseases that aren't inherited are Downs Syndrome, which is an extra chromosome on the number 21, it occurs in 1 in 650 births, often in women over 35, and Klinefelter's Syndrome, which is the presence of an extra x cromosome, ie XXY, it is a result of nondisjunction during gamete formation.
It depends on what's missing. Zygotes missing a chromosome (monosomy) have 45 chromosomes and many do survive; some human monosomies are monosomy 7, 11 or 13. A monosomy X results in Turner syndrome; there must be at least one X chromosome, or the embryo won't survive.
Meiotic nondisjunction. In meiosis I or II, chromosome pair 21 fail to separate correctly, leaving one gamete with an extra chromosome 21.
how could a zygote end up with an extra chromosome Either the egg or the sperm doesn't divide equally.
Trisomy occurs when an individual has three copies of a particular chromosome instead of the usual two. This can happen during the formation of sperm or egg cells, leading to an extra copy of the chromosome in the resulting embryo. Trisomy can result in conditions like Down syndrome, where there is an extra copy of chromosome 21.
Down Syndrom