Two significant technical challenges in gene therapy are effective delivery systems and immune response. Delivering therapeutic genes directly to target cells without causing harm to healthy tissues remains a complex task, often requiring sophisticated vectors like viral carriers. Additionally, the body's immune system may recognize these vectors or the introduced genes as foreign, leading to an immune response that can reduce the therapy's effectiveness and pose safety risks.
gene therapy/ Polygenic trait
one disadvantage is that when you come to know that you have a defected gene which could cause some disease/disorder, you have 2 options. go in for a very expensive treatment or go on with life knowing that you have a disease. many ppl dun have the money to spend on the expensive treatments. the second thing is it can be used for not-so-important purposed, like looking younger, being tall, having a smaller nose etc..again its controversial...is baldness enough a reason to carry out gene therapy as comaperd to cancer? also, many ppl have a prob wid prenatal screening (to find defective genes in the baby when you're pregnant). there are many legal, and ethical issues. depending on the type of gene therapy, der r disadvantages and advantages for each method used to administer gene therapy. having said all that, gene therapy gives someone with a disease a chance to live a normal life!
Gene therapy is a treatment of disease by replacing genes. Recombinant DNA is a DNA resulting from gene-linking. That is when a DNA extracted from two or more different sources such as genes from different organisms and joined together to form a single molecule or fragment.
A gene with two different alleles is called a heterozygous gene. This means that an individual has inherited two different versions of the gene, one from each parent.
Gene therapy is a treatment of disease by replacing genes. Recombinant DNA is a DNA resulting from gene-linking. That is when a DNA extracted from two or more different sources such as genes from different organisms and joined together to form a single molecule or fragment.
If a person is lacking a gene that causes a disorder, for example Diabetes, and a gene can be inserted into cells that require the gene, this would be gene therapy. Parkinson's disease and X-linked SCID are two that are be researched.
Gene therapy is a method that aims to cure inherited diseases by providing the patient with correct copy of the defective gene. There are four potential approaches to gene therapy:1)Addition of normal gene to replace the function of defective gene. This is gene replacement orgene augmentation therapy.2)Replacing the defective gene with the correct gene. This isCorrective gene therapy.3)Establishment of alternative pathways that bypass mutant genes function4)Change in regulation of normal or mutant genesThe first two are the basic approaches in gene therapy
Gene therapy is a method that aims to cure inherited diseases by providing the patient with correct copy of the defective gene. There are four potential approaches to gene therapy:1)Addition of normal gene to replace the function of defective gene. This is gene replacement orgene augmentation therapy.2)Replacing the defective gene with the correct gene. This isCorrective gene therapy.3)Establishment of alternative pathways that bypass mutant genes function4)Change in regulation of normal or mutant genesThe first two are the basic approaches in gene therapy
gene therapy/ Polygenic trait
If a person is lacking a gene that causes a disorder, for example diabetes, and a gene can be inserted into cells that require the gene, this would be gene therapy. Parkinson's disease and X-linked SCID are two that are be researched.
Precisely, gene therapy is applied under two strategies; 1. Therapeutic gene strategy 2. Gene therapy for replacing a mutated gene Therapeutic gene strategy involves the insertion/administration of DNA that encodes a therapeutic protein packaged within a "vector", into the body. Inside the body, the DNA becomes expressed by the cell machinery, resulting in the production of therapeutic protein, which in turn treats the patient's disease. Gene therapy for replacing a mutated gene involves the insertion of a functional gene (cloned into a vector) and administered into the body, where the functional gene express to neutralize the mutational effect.
one disadvantage is that when you come to know that you have a defected gene which could cause some disease/disorder, you have 2 options. go in for a very expensive treatment or go on with life knowing that you have a disease. many ppl dun have the money to spend on the expensive treatments. the second thing is it can be used for not-so-important purposed, like looking younger, being tall, having a smaller nose etc..again its controversial...is baldness enough a reason to carry out gene therapy as comaperd to cancer? also, many ppl have a prob wid prenatal screening (to find defective genes in the baby when you're pregnant). there are many legal, and ethical issues. depending on the type of gene therapy, der r disadvantages and advantages for each method used to administer gene therapy. having said all that, gene therapy gives someone with a disease a chance to live a normal life!
In biotechnology, vectors can include plasmids, bacteriophages, and viral vectors. These vectors are used to transfer genetic material into host cells for various applications such as gene cloning, gene therapy, and protein production. Plasmids are commonly used in recombinant DNA technology, while viral vectors are often used in gene therapy.
Gene therapy is a treatment of disease by replacing genes. Recombinant DNA is a DNA resulting from gene-linking. That is when a DNA extracted from two or more different sources such as genes from different organisms and joined together to form a single molecule or fragment.
People have to confront possibilities that didn't exist before. Gene therapy and life-support machines are two examples.
An indiviual letter in a punnett square representing a gene is called an allele. The two genes ( one from each parent ) together is a genotype. There isn't really two forms of a gene.
The two different molecular forms of a gene are called alleles.