a change in the sequence of amino acids. -P
a change in the sequence of amino acids determined by a gene
A silent mutation, where a change in the DNA sequence does not result in a change to the amino acid sequence of the protein, is likely to have the least effect on an organism. This is because the protein produced is unaffected, and therefore the organism's functioning remains unchanged.
B. The amino acid sequence may be altered during protein synthesis.
A frameshift mutation, where nucleotides are inserted or deleted in a gene sequence, is more likely to result in a nonfunctional protein because it disrupts the reading frame of the gene, leading to a completely different amino acid sequence. This can have a significant impact on the structure and function of the resulting protein.
The primary structure of the protein, which refers to the sequence of amino acids, would likely not be affected when a protein is denatured. Denaturation usually disrupts the secondary, tertiary, and quaternary structures of a protein.
This change was most likely caused by a point mutation called a missense mutation. Missense mutations involve the substitution of a single nucleotide in the DNA sequence, leading to a change in one amino acid in the protein sequence. In this case, the substitution of a single nucleotide led to the change from tyrosine to histidine in the protein sequence.
a change in the sequence of amino acids determined by a gene
sequence of subunits in DNA.
A silent mutation, where a change in the DNA sequence does not result in a change to the amino acid sequence of the protein, is likely to have the least effect on an organism. This is because the protein produced is unaffected, and therefore the organism's functioning remains unchanged.
sequence of subunits in DNA.
A single change in the primary sequence of bases can result in complete misfolding of proteins. The most likely serious change would be addition or deletion of a base, a substitution would be less likey to be as serious but can also render a protein inactive.
B. The amino acid sequence may be altered during protein synthesis.
This would result in a frameshift mutation. This would cause the protein, after translation, to be truncated and would most likely be non-functional. This is due to a change in the amino acid sequence and would stop the protein from forming the correct secondary and tertiary structures due to a change in the electrostatic/ hydrophobic/ h-bonding etc. parameters of the protein
A frameshift mutation, where nucleotides are inserted or deleted in a gene sequence, is more likely to result in a nonfunctional protein because it disrupts the reading frame of the gene, leading to a completely different amino acid sequence. This can have a significant impact on the structure and function of the resulting protein.
No. Since a mutation in the DNA may not necessarily result in a change to the encoded amino acid in the protein sequence, it is entirely possible. Further, the protein function will likely not change when an amino acid is replaced with one of similar chemical properties. Sometimes it does, sometimes it doesn't. This is the field that molecular evolutionary biologists study.
The primary structure of the protein, which refers to the sequence of amino acids, would likely not be affected when a protein is denatured. Denaturation usually disrupts the secondary, tertiary, and quaternary structures of a protein.
This mutation would cause a frameshift mutation, shifting the reading frame of the DNA sequence. Most likely, this would lead to a completely different protein being translated, resulting in a protein with a different sequence of amino acids from the original protein. The number of amino acids would depend on the specific changes in the protein sequence caused by the frameshift mutation.