What determines how protein polypeptides fold into 3-dimensional structures?

Answer 1

The linear arrangement of the constituent amino acid subunits. All twenty amino acids have the same base, but all have different R groups that have different classes of bonding. Some R groups are hydrophobic, some are hydrophyllic, some are acidic, some are thiols and some ore basic. So, all different types of folding of the tertiary structure of polypeptides are possible and due to the combinatorial arrangement of the twenty amino acids hundreds of thousands of different protein foldings are possible. And in proteins form equals function.

Answer 2

All of these:

the sequence of the amino acids,

how amino acids interact with water, and

how amino acids interact with each

other.

My sources: I got it right on my quiz. (:

Answer 3

The primary structure of a protein, which is the sequence of amino acids, determines how it will fold into a 3-dimensional shape. This folding is influenced by various factors such as hydrogen bonding, hydrophobic interactions, disulfide bonds, and electrostatic interactions between amino acids. Additionally, chaperone proteins can assist in the proper folding of proteins.

Answer 4

By how the amino acids in the "arms" of the protein interact with water and one another.