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Causes a shift in the reading codons by one base?
A frameshift mutation is caused by the insertion or deletion of a nucleotide in the DNA sequence, leading to a change in the reading frame of codons. This can result in a completely different protein being produced from the altered sequence, affecting the functionality of the protein.
When a nitrogenous base is inserted or delete how does that affect the amino acid sequence?
The amino acid sequence is shifted, and this kind of mutation is called a frame shift mutation. All of the amino acid sequence after the mutation will be changed, which will cause a change in shape of the protein, which will then probably result in a nonfunctional protein, since the shape of a protein determines its function.
Which type of mutation would have a greater effect on the sequence of amino acids in a protein a base-pair substitution or a frame shift mutation?
Point mutations are normally single base substitutions in a DNA strand. For example:Imagine this is a DNA strand split up into 3 bases.Instead of: The fat cat ate the wee rat and hatYou will get: The fat bat ate the wee rat and hatThere is not much of a change. It may result in a different amino acid being placed there when it is translated.Frameshift mutations on the other hand are much more devastating.Instead of: The fat cat ate the wee rat and hatYou will get: The fat bca tat eth ewe era tan dha tYou can see that the addition (or even deletion) of one base changes EVERYTHING after it. Therefore, most of the amino acids will be different than the ones intended when it is translated.Therefore, frameshift mutations have the large effect.
How many amino acids would this protein have if a mutation occurred and the 7th dna base pair of the dna strand was changed from a-t to t-a?
This mutation would cause a frameshift mutation, shifting the reading frame of the DNA sequence. Most likely, this would lead to a completely different protein being translated, resulting in a protein with a different sequence of amino acids from the original protein. The number of amino acids would depend on the specific changes in the protein sequence caused by the frameshift mutation.
What is the difference between a nonsense mutation and a missense mutation?
Missense mutation: changes one sense codon to another, resulting in incorporation of amino acid.Nonsense mutation: changes a sense codon into a stop (or nonsense) codon, resulting in premature termination.
Which of the following is a point mutation that does not produce a frame shift?
A point mutation that does not produce a frame shift is when one single base is replaced by a different base. This changes the DNA sequence, but does not cause a frame shift because it is a switch not an addition or subtraction of a base.
Was the sequence a result of point or frame shift mutation?
No
Would a point mutation or a frame shift mutation more likely produce a neutral mutation?
A point shift mutation is more likely to produce a neutral reaction. This is because it involves a change in one nucleotide. A frame shift mutation is more deleterious because it involves the insertion or deletion of multiple base pairs within a gene's coding sequence.
Causes a shift in the reading codons by one base?
A frameshift mutation is caused by the insertion or deletion of a nucleotide in the DNA sequence, leading to a change in the reading frame of codons. This can result in a completely different protein being produced from the altered sequence, affecting the functionality of the protein.
What type of mutation when a nucleotide is dropped from a DNA sequence?
A deletion mutation occurs when a nucleotide is dropped from a DNA sequence. This can cause a shift in the reading frame, leading to a non-functional protein being produced.
When a nitrogenous base is inserted or delete how does that affect the amino acid sequence?
The amino acid sequence is shifted, and this kind of mutation is called a frame shift mutation. All of the amino acid sequence after the mutation will be changed, which will cause a change in shape of the protein, which will then probably result in a nonfunctional protein, since the shape of a protein determines its function.
A mutation in which a single base is added to or deleted from DNA is called what?
A mutation in which a single base is added to or deleted from DNA is called an insertion or deletion mutation, also known as an indel mutation. This can lead to a shift in the reading frame during translation, causing significant changes in the resulting protein sequence and potentially leading to functional consequences.
Name two major types of mutations?
Frameshift mutations and Point mutations. The difference between the two are that point mutations occur at a single point in the DNA sequence and frameshift mutations shift the "reading frame" of the genetic message.
During DNA replication an extra cytosine base is added to the DNA What type of Mutation is this-?
Frameshift mutation
During DNA replication an extra cytosine base is added to the DNA what type of mutation is this?
A frameshift mutation
What is frame shift?
A frame shift mutation is one in which the "reading frame" for protein synthesis is altered. Starting from the DNA, you have either the insertion or deletion of one or more base pairs (but not in a multiple of three). For example, onebase pairmay be inserted into the coding portion of a gene. This is transcribed into mRNA then taken to the ribosome to be "read" (translated) by the tRNA. However, tRNA has three bases on the end of it, which correspond to a specific amino acid. By adding one base into the sequence, you "shift" the reading frame by one base pair and completely change the entire remaining amino acid sequence. Note that if you were to add or subtract three (or a multiple of three) base pairs, you would not shift the frame - you would add or subtract amino acids, but the remaining ones would be the same as the original sequence.
What are two types of frame shift mutations?
"I believe there is insertion and deletion, (one kind), and substitutions. (the second kind)" This answer is incorrect, the two types of frameshift mutation are insertion and deletion, these both alter the translation reading frame. A substitution point mutation in DNA is referred to as a single-nucleotide polymorphism and does not result in any change to the translational reading frame. insections and deletions are two types of frameshift mutations
