Transcription factors bind to specific DNA sequences in the promoter region, helping to position the initiation complex. These transcription factors recruit RNA polymerase to the promoter, facilitating the assembly of the initiation complex. The correct positioning of the initiation complex is essential for the efficient initiation of transcription.
A promoter is a segment of DNA that helps RNA polymerase recognize the start of a gene.
Transcription factors are regulatory proteins in eukaryotes that control the initiation of transcription by binding to specific DNA sequences near genes and either activating or repressing their transcription. This binding helps regulate the expression of genes by influencing the binding of RNA polymerase to the promoter region of a gene.
Transcription factors bind in this order: D, A, B, F, E, H, J.RNA polymerase (usually RNA pol II for transcription fo protein coding genese) binds with TFIIF.DetailsInitially, TFIID binds to the TATA box of the DNA strand, if present, since the TBP is part of the TFIID complex. The shape of TBP causes large changes in the shape of the DNA molecule, unwinding it greatly. This allows TFIIA and then TFIIB (with TFIID) to bind to the promoter region, followed by TFIIF (similar to sigma factor in prokaryotes) with RNA polymerase II, then TFIIE, which enables the polymerase to move along the DNA easily, and TFIIH, which contains a helicase to unwind the DNA and an enzyme region to phosphorylate (initiating elongation) a region of the polymerase II enzyme known as the C terminal domain (which is unique to this form of polymerase II). This forms a complex known as the basal transcription apparatusOther transcription factors may also bind depending on the specific gene being transcribed. TBP binds specifically to the TATA box, and in the case of the large number of genes that do not use the TATA consensus sequence this will be replaced by that gene's alternative.For further information on the structure of the completed complex, I recommend the structure of the RNA polymerase II elongation complex to 3.3 angstroms as determined by Gnatt et al.
The active CAP (catabolite activator protein) binds to the CAP site near the promoter of the lactose operon. This binding helps RNA polymerase bind to the promoter, leading to enhanced transcription of the genes in the lactose operon. This process is a part of positive regulation in response to low glucose levels and presence of lactose.
Transcription factor A binds to specific DNA sequences called promoter regions to initiate the transcription of a gene. It helps RNA polymerase recognize the promoter and start transcribing the gene into mRNA. Transcription factor A plays a crucial role in regulating gene expression by controlling when and how much mRNA is produced.
True. The TATA box is a DNA sequence found in the promoter region of many eukaryotic genes. It helps to recruit transcription factors and RNA polymerase to the promoter, facilitating the initiation of transcription.
A promoter is a region of DNA that signals the start of a gene. It plays a crucial role in initiating gene expression by attracting RNA polymerase, the enzyme responsible for transcribing the gene into RNA. The promoter helps RNA polymerase bind to the DNA and begin the process of transcription, which is the first step in the expression of a gene.
In eukaryotes, the TATA-binding protein (TBP) is involved in promoter recognition. TBP is a subunit of the transcription factor II D (TFIID) complex, which binds to the TATA box within the promoter region of genes and helps initiate transcription.
The Tata box is a DNA sequence that helps in the initiation of gene transcription by providing a binding site for transcription factors. It plays a crucial role in the regulation of gene expression by facilitating the assembly of the transcription machinery at the promoter region of a gene.
The promoter region in DNA helps RNA polymerase recognize the start of a gene. The promoter contains specific sequences that serve as binding sites for RNA polymerase, allowing it to initiate transcription of the gene. Transcription factors also play a role in assisting RNA polymerase in recognizing and binding to the promoter region.
when RNA Polymerase meet the correct promoter(TATA box), it will bind at that region and then sigma factor will also bind to the RNA Polymerase.once ATP give energy, sigma factor will dissoiates from RNA Polymerase and the enzyme start to unwind the double helix
The TATA box seems to help position RNA polymerase by marking a point just before the point at which transcription begins.
The gene expression is regulated from transcriptional initiation, to RNA processing, and to the post-translational modification of a protein. The regulation of the genes helps to either decrease or increase the production of a specific gene products.
The TATA box assists in directing RNA polymerase II to the initiation site downstream on DNA. RNA polymerases bind to regions of DNA known as promoters. Promoter regions are comprised of the initiation site and numerous nucleotides upstream from the initiation site. The TATA box is necessary for transcription because RNA polymersase II cannot recognize the initiation sites on its own.
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A promoter is a segment of DNA that helps RNA polymerase recognize the start of a gene.