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It is an anti-rejection medication used in Transplant Patients. It can also used in some severe cases of rheumatoid arthritis and other conditions.
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What is another name for Cyclosporine?
Another name for Cyclosporine is Sandimmune.
How are fungi related to cyclosporine?
Cyclosporine is a drug derived from a fungus called Tolypocladium inflatum. Fungi produce this compound as a defense mechanism against other microorganisms. It is used in medicine as an immunosuppressant to prevent organ rejection in transplant patients.
Who discovered cyclosporine?
Cyclosporine was discovered by a team of researchers led by Hartmann F. Stähelin and Jean-François Borel in Switzerland in 1970. They were studying soil samples for potential antibiotic properties and identified cyclosporine as a compound produced by the fungus Tolypocladium inflatum.
What drug is Cyclosporine produced from?
Ciclosporin, cyclosporine or cyclosporin is an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system and, so, the risk of organ rejection. Initially isolated from a Norwegian soil sample, Ciclosporin A, the main form of the drug, is a cyclic nonribosomal peptide of 11 amino acids (an undecapeptide) produced by the fungus Beauveria nivea, and contains a single D-amino acid, which are rarely encountered in nature. Cyclosporine A is synthesized by a nonribosomal peptide synthetase, cyclosporine synthetase. The enzyme contains an adenylation domain, a thiolation domain, a condensation domain, and an N-methyltransferase domain. The adenylation domain is responsible for substrate recognition and activation, whereas the thiolation domain covalently binds the adenylated amino acids to phosphopantetheine and the condensation domain elongates the peptide chain. Generic ciclosporin preparations have been marketed under various trade names including Cicloral (Sandoz/Hexal) and Gengraf (Abbott). Numbnuts just get straight to the damn answer the answer is Imperfect Fungi don't read all the useless crap
What can inhibit lipase?
Orlistat is one chemical that can inhibit the activity of enzyme lipase. Higher version of orlistat which is only available through prescription is Xenicol. There are several enzymes that break down fat molecules in our food so it can be used/stored in our body. Certain drugs resist the activity of those enzymes and fat is passed through the system unabsorbed.
Who is the manufacturer of cyclosporine?
Can I get financial aide for the medicine Cyclosporine, my insurance does not cover it.
What is another name for Cyclosporine?
Another name for Cyclosporine is Sandimmune.
Can cyclosporine harm baby when pregnant?
Can cyclosporine harm the baby while 31 weeks pregnant?
What is the dosage for cyclosporine?
In general, cyclosporine is taken every 12 hours in liquid or capsule form.
How are fungi related to cyclosporine?
Cyclosporine is a drug derived from a fungus called Tolypocladium inflatum. Fungi produce this compound as a defense mechanism against other microorganisms. It is used in medicine as an immunosuppressant to prevent organ rejection in transplant patients.
Briefe account on cyclosporine?
Cyclosporine suppresses T cells, which would otherwise tend to attack the tissues of a transplanted organ.
What is another name for Sandimmune?
Cyclosporine
What is the generic name for Sandimmune?
cyclosporine
Who discovered cyclosporine?
Cyclosporine was discovered by a team of researchers led by Hartmann F. Stähelin and Jean-François Borel in Switzerland in 1970. They were studying soil samples for potential antibiotic properties and identified cyclosporine as a compound produced by the fungus Tolypocladium inflatum.
Side effects of general anesthesia cyclosporine predisonole?
Effects of Cyclosporine on Anesthetic Action Vincent N. Cirella, MD, Carol B. Pantuck, BA, Young Joo Lee, MD, PhD, and Eugene J. Pantuck, MD Received from the Department of Anesthesiology, College of Physicians and Surgeons, Columbia University, New York, New York. Abstract The effects of a single dose of cyclosporine on anesthetic actions of pentobarbital and fentanyl were studied in mice. Mice given pentobarbital 2 hr after receiving cyclosporine, 60 mg/kg, slept a statistically significant 2.3 times longer than did controls. In a second study, each of two dose levels of cyclosporine was given before each of four dose levels of fentanyl. The analgesic effect of fentanyl, measured with the abdominal constriction test, was dose-dependent. Cyclosporine significantly increased the analgesia produced by fentanyl and did so in a dose-dependent manner. Cyclosporine by itself did not produce analgesia. Plasma levels of fentanyl and binding of fentanyl by plasma proteins were unchanged by cyclosporine treatment. The results show that a single dose of cyclosporine can increase pentobarbital hypnosis and fentanyl analgesia in mice but do not establish the mechanism of these interactions. Key Words: IMMUNE RESPONSE, SUPPRESSION—cyclosporine • INTERACTIONS (DRUG)—cyclosporine, anesthetics
How do you dilute cyclosporine?
To dilute cyclosporine, use a compatible diluent such as 0.9% sodium chloride injection or 5% dextrose injection. Slowly add the diluent to the vial and gently mix the solution to ensure proper dispersion. Follow specific dilution instructions provided by the manufacturer or pharmacist.
What are the normal ranges for a Cyclosporine test?
100 to 200 ngm
