Apparatus 3 Modified a dissolution apparatus used to study in-vitro dissolution behaviour of solid dosage forms, particularly modified release dosage forms.
The Golgi Apparatus modifies and packages proteins.
From the Endoplasmic reticulum, proteins travel to the Golgi Apparatus to be modified and packaged.
basic principal of dissolution run as per individuala monograph and know the % of active drugs in sample
The modified proteins are then enclosed in new vesicles that bud from the surface of the Golgi apparatus.
Cell products are modified and packaged for transport in the Golgi apparatus within the cell. The Golgi apparatus receives proteins and other materials from the endoplasmic reticulum, modifies them, and then packages them into vesicles for transport to various destinations within and outside the cell.
The two common types of dissolution apparatus used for drug dissolution testing are the USP apparatus I (basket) and USP apparatus II (paddle). The basket apparatus is recommended for capsules and floating dosage forms, while the paddle apparatus is typically used for tablets and other solid dosage forms. Both apparatus are designed to simulate the conditions of the gastrointestinal tract to assess drug release characteristics.
The limit of temperature in dissolution apparatus typically depends on the specific apparatus being used. In general, most dissolution apparatus can operate within a temperature range of 30-40°C. However, there are specialized apparatus that can handle higher temperatures up to 50-60°C for specific applications. It is important to consult the manufacturer's guidelines for the specific apparatus being used to determine the temperature limits.
I believe it is the Golgi Apparatus.
By dissolution the chemical structure is not modified.
Proteins are modified after they are made in the endoplasmic reticulum and Golgi apparatus within the cell.
Golgi apparatus
the products are energy, carbon dioxide, and water.
The Golgi Apparatus modifies and packages proteins.
In the golgi apparatus
Cell products are modified and packaged in vesicles for transportation in Golgi apparatus.
The Golgi Apparatus modifies and packages proteins.
The modified proteins are then enclosed in new vesicles that bud from the surface of the Golgi apparatus.