0
To explain it in the simplest way i can think of, explained by a doctor in the Academy Award Winning movie Lorenzo's Oil, Myelin is like the rubber part on an electrical cord that gives it energy in some way (not sure how) and ALD or Adrenoleukodystrophy, affects it by eroding that part of it. I'm not sure though how this affects the bodies brain functions.
What else can I help you with?
How does the degereration of the myelin sheaths on cells in the white matter of the central nervous system result in the impaired brain functions in ALD patients?
Myelin sheaths in the central nervous system do the same basic job as they do in the peripheral nervous system. They insulate the axons, which are the conducting parts of nerve cells, so that they can carry their signal better. When this protective mechanism is damaged, as in ALD, the nerve cells cannot communicate properly and result in the signs and symptoms of ALD. Unfortunately this genetic disorder not usually caught in its early stages to provide effective treatment.
Who discovered ald?
The discovery of ald is attributed to PerkinElmer in 2009. Ald stands for Amplified Luminescent Proximity Homogeneous Assay, which is a versatile technology used in life science research for detecting biomolecules in a homogenous format.
What are schwann cell nucleus'?
myelin sheath peace.love.faith
What is myelin sheath on nerve fibers?
The endoneurium surrounds and protects the myelin sheath.
What is the genotype of an ALD boy?
The genotype of an ALD (adrenoleukodystrophy) boy is typically X-linked recessive. This means that the boy has a mutation on the X chromosome, which is responsible for the development of the disease. Typically, the genotype is represented as XL for an affected boy.
What is adrenoleukodystrophy?
Adrenoleukodystrophy (ALD) is a genetic disorder that affects the nervous system and adrenal glands. It is characterized by the buildup of fatty acids in the body due to a defect in a specific enzyme that breaks them down. ALD can lead to damage to the myelin sheath, which is the protective covering of nerve cells, resulting in progressive neurological problems.
How does nicotine affect the myelin production?
Nicotine stimulates CREB phosphorylation which regulates the expression of myelin basic protein and myelin oligodendrocyte glycoprotein.
How does the degereration of the myelin sheaths on cells in the white matter of the central nervous system result in the impaired brain functions in ALD patients?
Myelin sheaths in the central nervous system do the same basic job as they do in the peripheral nervous system. They insulate the axons, which are the conducting parts of nerve cells, so that they can carry their signal better. When this protective mechanism is damaged, as in ALD, the nerve cells cannot communicate properly and result in the signs and symptoms of ALD. Unfortunately this genetic disorder not usually caught in its early stages to provide effective treatment.
After several months of ALD what does Lorenzo's neuron look like?
It has lost its myelin sheath (clothes) so it can no longer be used to send messages from the brain to other parts of the body.
Does a nervous breakdown affect the myelin sheaths?
No. It does not. It can not. It neither affect the neurons also.
What does demyelination affect?
The myelin sheath that surrounds the nerve
What is the prognosis for a person with adrenoleukodystrophy?
Prognosis for childhood and neonatal ALD patients is poor because of the progressive myelin degeneration. Death usually occurs between one and ten years after onset of symptoms.
Does simvastatin affect the myelin sheath?
yes, in many ways
What does ALD do to the white matter in the brain?
Myelin sheaths in the central nervous system do the same basic job as they do in the peripheral nervous system. They insulate the axons, which are the conducting parts of nerve cells, so that they can carry their signal better. When this protective mechanism is damaged, as in ALD, the nerve cells cannot communicate properly and result in the signs and symptoms of ALD. Unfortunately this genetic disorder not usually caught in its early stages to provide effective treatment.
Why is a disease like ALD much more common in boys than in girls?
The most common type of ALD (adrenoleukodystrophy) is X-linked ALD. Than means that the gene for ALD is on the X chromosome. Because boys have only one X chromosome, if it has the ALD gene on it they will have the disease. Girls have two X chromosomes, so, in order to get ALD both of their X chromosomes would have to have an ALD gene. That would mean that both her father and her mother would have to have an ALD gene. Because males with ALD die before they can have children this would not happen. So girls don't get this type of ALD. There are other, more rare types of ALD that affect both boys and girls. So, all in all, fewer girls have ALD
What was the purpose of the ald symposium in lorenzo's oil?
To have scientists collaborate to help find a therapy for ALD
What does ALD do to a person?
You are requested to write the long form of the 'ALD' and write back the question.
