A non-genomic pathway is a signaling pathway that does not involve changes in gene expression. Instead, it typically involves rapid responses to extracellular signals, such as changes in ion fluxes or activation of kinase cascades, leading to rapid cellular responses. This pathway is independent of gene transcription and translation.
Feedback inhibition at the beginning of a metabolic pathway allows for rapid control of the pathway by regulating the initial enzyme activity, helping to prevent unnecessary accumulation of intermediates. This control mechanism is more efficient and direct compared to inhibiting enzymes in the middle of the pathway, which may lead to wasteful buildup of metabolites before regulation occurs.
This phenomenon is known as feedback inhibition, where the final product of a biochemical pathway binds to the enzyme responsible for an early step in the pathway, inhibiting its activity. This mechanism helps regulate the overall rate of the pathway, ensuring that the cell does not produce excessive amounts of the final product.
The extrinsic pathway shortcut allows for a rapid response to tissue injury by activating factor X directly, leading to a quicker initiation of the coagulation cascade. The multiple steps of the intrinsic pathway provide amplification of the coagulation response, resulting in a more robust clot formation and greater sensitivity to stimuli.
The neural pathway of a single reflex is called a reflex arc. It involves the sensory neuron carrying information from the receptor to the spinal cord, where it synapses with a motor neuron that carries the response signal to the effector muscle or organ. This simple pathway allows for rapid, involuntary responses to stimuli.
A non-genomic pathway is a signaling pathway that does not involve changes in gene expression. Instead, it typically involves rapid responses to extracellular signals, such as changes in ion fluxes or activation of kinase cascades, leading to rapid cellular responses. This pathway is independent of gene transcription and translation.
activation-synthesis model
Feedback inhibition at the beginning of a metabolic pathway allows for rapid control of the pathway by regulating the initial enzyme activity, helping to prevent unnecessary accumulation of intermediates. This control mechanism is more efficient and direct compared to inhibiting enzymes in the middle of the pathway, which may lead to wasteful buildup of metabolites before regulation occurs.
Reflexes are rapid involuntary responses to a given stimuli. The reflex pathway that only has one synapse in the CNS is called the monosynaptic reflex arc.
Sub- refers to below or under, cortical refers to the superficial (top) layer of a tissue/organ/structure; subcortical means the tissue/organ/structure just under the cortical layer. A common use of this term is "subcortical bone", which refers to the bone marrow.
A subcortical cyst is a type of cyst that develops on the skeletal frame in the body. Depending on the location, they can be benign, but they can also early indicators of some diseases.
This phenomenon is known as feedback inhibition, where the final product of a biochemical pathway binds to the enzyme responsible for an early step in the pathway, inhibiting its activity. This mechanism helps regulate the overall rate of the pathway, ensuring that the cell does not produce excessive amounts of the final product.
An abnormal, rapid heart rhythm, due to an extra pathway for the electrical impulses to travel from the atria to the ventricles.
The extrinsic pathway shortcut allows for a rapid response to tissue injury by activating factor X directly, leading to a quicker initiation of the coagulation cascade. The multiple steps of the intrinsic pathway provide amplification of the coagulation response, resulting in a more robust clot formation and greater sensitivity to stimuli.
The simplest pathway of an impulse involves the sensory neuron transmitting a signal to the interneuron in the spinal cord, which then relays the signal to the motor neuron, causing a response in a muscle or gland. This pathway is known as a reflex arc and allows for rapid, automatic responses to stimuli without involving the brain.
Cotton
Heparin, the natural anticoagulant contained in basophil and mast cell granules. It inhibits thrombin by enhancing the activity of antithrombin III. Heparin also inhibits the intrinsic pathway. antithrombin III and protein c inhibit the activity of other intrinsic pathway procoagulants.