Amprolium is not an organism, so is not an antibiotic in the sense I think you mean. It is an analog of Vitamin B1, and works by preventing the uptake of thiamine (B1) by the organism which causes coccidiosis. Amprolium makes the creature's body an environment hostile to the development of coccidiosis, without actually attacking the coccidiosis organism. It's like a placebo food for the coccidiosis microbe, which gets no nourishment from it. To some degree amprolium also reduces the uptake of thiamine in the creature who is eating amprolium in its feed, so it is only administered until the young chickens are old enough to have built up an immunity to coccidiosis, from low-level environmental exposure to it. Then they are switched to unmedicated feed. (This is fairly common for management of small poultry flocks; I can't speak about the management of large-scale operations.) Using amprolium does not contribute to drug-resistant microbes.
Yes, drug resistance genes can be carried on plasmids, which are small, circular DNA molecules found in bacteria. Plasmids can be easily transferred between bacteria, spreading drug resistance within a population. This transfer of plasmids contributes to the development of antibiotic-resistant bacterial strains.
Bacterial populations can develop drug resistance through mutations that make them less susceptible to antibiotics. They can also acquire resistance genes from other bacteria through mechanisms like conjugation, transformation, or transduction, allowing them to share resistance traits. This exchange of genetic material can lead to the rapid spread of drug resistance among bacterial populations.
When a drug is administered, it is given at a prescribed dose so the active ingredient can bind and inhibit a particular enzyme, or target. Gene amplificatin increases the amount of copies of a particular area of chromosome and thus increases the amount of mRNA which will be transcribed. If the target is amplified over and over, it reaches a point to where the drug is not binding to enough of the substrate to be effective. Essentially, gene amplification dilutes a normal dose and in order to combat it, higher dosages are needed.
Drug resistance in bacteria can be harmful to humans because it can result in less effective treatments for infections. Higher doses may be needed to treat infections, and so treatment may have more risks. In some cases, antibiotics may no longer be effective at all.
Individual pathogens can develop resistance to antimicrobial drugs through several mechanisms. These include acquiring genes that code for drug resistance, mutations that render the drug targets less susceptible to the drugs, and the ability to pump out or destroy the drugs. These adaptations occur through genetic changes that give the pathogens a survival advantage and allow them to evade the action of the drugs.
Speaking for common small-flock management...not sure what the large-scale operation practice is. Layer chicks are often raised on medicated chick starter, the relevant ingredient of which is amprolium, which is to prevent coccidiosis. (Amprolium is an analog for Vitamin B1 and is not an organism, itself.) The amprolium keeps the coccidiosis microbe at bay in the chicks' bodies until, at eight or nine weeks, the chicks have developed a resistance to coccidiosis from low-level environmental exposure to it, and do not need the amprolium any more, so are switched to unmedicated feed. Hens typically don't start laying until twenty weeks of age, so there is no reason why a laying hen would be eating amprolium-medicated feed any more, anyhow.
Drug Abuse Resistance EducationThank you for your apprecitation
exactly what it says. it is a mechanism that confers drug resistance to microbes. exactly what it says. it is a mechanism that confers drug resistance to microbes.
Drug Abuse Resistance Education was created in 1983.
Amprolium HCl is used to treat coccidiosis of laying hens, growing chickens, turkey, cattle's and different other farm animals, also used as assistance treatment drugs to prevent and control the coccidiosis' spread. Amprolium Hydrochloride is traditional coccidiostatic, and it's used in poultry feed to control coccidiosis. Amprolium Hydrochloride is very good against the hemorrhage-producing coccidia E. tenella and E. necatrix and it has some activity against E. maxima, amprolium hydrochloride is one of the most safety anti-coccidial drugs and be approved by FDA.
Drug-resistant yeast infections, as the name implies, are yeast infections that have reached a stage where the infection, or the rather the cause of it, has managed to build-up a resistance to the drug-based medication(s) being used at the time.
Ethan G. Verrite has written: 'Drug resistant neoplasms' -- subject(s): Neoplasm Drug Resistance, Drug resistance in cancer cells
Amprolium, commonly known as Corid, is primarily used in cattle and poultry to treat coccidiosis and is not approved for use in horses. While it is generally considered safe for the species it is intended for, there is limited research on its effects in horses. Administering Amprolium to horses could potentially lead to adverse effects, so it is crucial to consult a veterinarian before using any medication not specifically approved for equine use.
drug resistance
Yes, drug resistance genes can be carried on plasmids, which are small, circular DNA molecules found in bacteria. Plasmids can be easily transferred between bacteria, spreading drug resistance within a population. This transfer of plasmids contributes to the development of antibiotic-resistant bacterial strains.
TREVOR
Bacterial populations can develop drug resistance through mutations that make them less susceptible to antibiotics. They can also acquire resistance genes from other bacteria through mechanisms like conjugation, transformation, or transduction, allowing them to share resistance traits. This exchange of genetic material can lead to the rapid spread of drug resistance among bacterial populations.