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What is the Classification of Etoricoxib?
this etoricoxib has solubility problem and good permeation so must be BCS(biopharmaceutical classification sysytem)-II ok bye srinivasan krupanidhi college of pharmacy Bangalore 9535307023
Which portion aspirin molecule is responsible for its therapeutic effect?
The acetyl group in the aspirin molecule is responsible for its therapeutic effect. Aspirin works by inhibiting an enzyme called cyclooxygenase, reducing the production of inflammatory chemicals called prostaglandins. This helps reduce pain, fever, and inflammation.
What is the classification of an enzyme that catalyzes the joining of two molecules?
Enzymes that catalyze the joining of two molecules are classified as ligases. Ligases are a type of enzyme that catalyze the formation of bonds between molecules, typically through the hydrolysis of ATP or other high-energy molecules to drive the reaction.
A protein catalyst is known as an?
Enzyme.
What kind of molecule is an enzyme-?
The type of molecule that is an enzyme is a protein molecule.
Where can one find information about Cyclooxygenase?
Cyclooxygenase (COX), the key enzyme required for the conversion of arachidonic acid to prostaglandins was first identified over 20 years ago. Drugs, like aspirin, that inhibit cyclooxygenase activity have been available to the public for about 100 years. In the past decade, however, more progress has been made in understanding the role of cyclooxygenase enzymes in biology and disease than at any other time in history. Two cyclooxygenase isoforms have been identified and are referred to as COX-1 and COX-2. Under many circumstances the COX-1 enzyme is produced constitutively (i.e., gastric mucosa) whereas COX-2 is inducible (i.e., sites of inflammation). Here, we summarize the current understanding of the role of cyclooxygenase-1 and -2 in different physiological situations and disease processes ranging from inflammation to cancer.
What is a cox?
The word cox is short for coxswain, the helmsman of a boat, especially of a racing crew.It is also an abbreviation for cyclooxygenase, an enzyme group active in the stomach and kidneys.
How do we know how Tylenol works?
Tylenol works by blocking pain signals in the brain. It does this by inhibiting an enzyme called cyclooxygenase, which reduces the production of prostaglandins, chemicals that cause pain and inflammation.
How does aspirin work to inhibit platelet aggregation?
Aspirin works by blocking an enzyme called cyclooxygenase, which is needed for the production of certain chemicals that promote platelet aggregation. By inhibiting this enzyme, aspirin helps prevent platelets from sticking together and forming blood clots.
What does Cyclooxygenase 1 do?
Cyclooxygenase 1 is important for homeostatic maintenance such as platelet aggregation, the regulation of blood flow in the kidney and stomach, and the regulation of gastric acid secretion
Which drugs blocks the cyclooxygenase pathway in platelets?
aspirin
What is a prostaglandin hormone made from?
They are synthesized in the cell from the essential fatty acids (EFAs). An intermediate arachidonic acid is created from diacylglycerol via phospholipase-A2, then brought to either the cyclooxygenase pathway or the lipoxygenase pathway to form either prostaglandin and thromboxane or leukotriene respectively. The cyclooxygenase pathway produces thromboxane, prostacyclin and prostaglandin D, E and F. Alternatively, the lipoxygenase enzyme pathway is active in leukocytes and in macrophages and synthesizes leukotrienes. Dr.Fabianski Benjamin
How does pain pills alliveate pain?
Common knowledge would tell you that all pain medications are the same, when in fact, there are several different classifications. Pain killers such as Acetaminophen and Iubprofen (which can be found over-the-counter) work by inhibiting an enzyme known as cyclooxygenase, this specific enzyme helps fatty acids reach a chemical in the body called prostaglandins (which produces pain, inflammation and fevers etc.) By blocking cyclooxygenase you therefore reduce the pain. Now, on the other hand, Narcotic pain killers like hydrocodone, oxycodone and morphine work by changing the way your body percieves pain. This type of medication is usually found in a combination that includes Acetaminophen or Iubprofen.
What role does cyclooxygenase play in pain and inflammation?
There are two types of Cox, theres Cox-1 and Cox-2. Cox-1 is an enzyme that helps regulate stomach acid and keep it in the stomach. While Cox-2 promotes inflammationin the body, now this is neccesarily a bad thing. Unless There becomes a high amount of Cox-2.
What is the Classification of Etoricoxib?
this etoricoxib has solubility problem and good permeation so must be BCS(biopharmaceutical classification sysytem)-II ok bye srinivasan krupanidhi college of pharmacy Bangalore 9535307023
Which portion aspirin molecule is responsible for its therapeutic effect?
The acetyl group in the aspirin molecule is responsible for its therapeutic effect. Aspirin works by inhibiting an enzyme called cyclooxygenase, reducing the production of inflammatory chemicals called prostaglandins. This helps reduce pain, fever, and inflammation.
How can you identify an enzyme by its name?
Enzyme names typically end in "-ase" and often suggest the substrate they act upon or the type of reaction they catalyze. Enzyme classification databases like the Enzyme Commission (EC) system can be used to systematically identify enzymes based on specific criteria. Additionally, scientific literature and bioinformatics resources can provide information on the properties and functions of specific enzymes based on their names.
