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What is the advantage of having multiple receptor subtypes for a neurotransmitter?
Multiple receptor subtypes allow for more "fine-tuned" neuromodulation of a given "signal" in a neural network. Each receptor subtype typically has a different binding affinity for the given neurotransmitter. Therefore, the neurotransmitter may bind more strongly or more weakly to one subtype over another. This is most likely an effect of genetic variation, as the genes coding for the protein(s) present in the receptor slightly vary from subtype to subtype, yet still allow for binding by the neurotransmitter ligand.
What determines whether a neurotransmitter will have an inhibitory excitatory effect?
How a neurotransmitter interacts with the receptors determines its effects. They activate receptors to perform specific functions in the body.the type of receptor
What does the neurotransmitter bind to after it moves across the synaptic cleft?
The neurotransmitter binds to specific receptors on the postsynaptic neuron's membrane. This binding triggers a series of events that can either excite or inhibit the postsynaptic neuron, ultimately influencing its activity.
The same receptor can have different effects depending on the properties of the?
ligand that binds to it. For example, a receptor can trigger different signaling pathways or cellular responses if it binds to different ligands, even if they bind to the same binding site on the receptor. This is known as ligand-dependent receptor activation.
How is the neurotransmitter acetylcholine inactivated at the parasympathetic terminal receptor site?
Acetylcholine is primarily inactivated at the parasympathetic terminal receptor site by the enzyme acetylcholinesterase. Acetylcholinesterase breaks down acetylcholine into choline and acetate, which are then taken back up by the presynaptic terminal for further use in neurotransmitter synthesis. This inactivation process allows for the rapid termination of acetylcholine signaling and helps maintain proper neurotransmitter balance in the synapse.
What adrenergic neurotransmitter receptor plays a role in heart activity?
beta neuron
Which structure is like a locked door that only certain neurotransmitter key can unlock?
Since only 1 neurotransmitter fits in the receptor sites, you can say that the receptor sites is the locked door waiting for the neurotransmitter "keys".
How do benzodiazepines interact with the GABA receptor to produce their therapeutic effects?
Benzodiazepines enhance the activity of the neurotransmitter GABA at its receptor in the brain, which leads to a calming and sedative effect. This interaction helps to reduce anxiety, promote relaxation, and improve sleep quality.
Which neurotransmitter inhibits pain transmission?
SEROTONIN is a neurotransmitter that inhibits pain by blocking pain causing chemicals out of their receptor sites
What is a molecule such as a neurotransmitter or a hormone that binds to a receptor called?
A molecule such as a neurotransmitter or hormone that binds to a receptor is called a ligand. This binding triggers a biological response in the target cell, influencing its function.
What is the advantage of having multiple receptor subtypes for a neurotransmitter?
Multiple receptor subtypes allow for more "fine-tuned" neuromodulation of a given "signal" in a neural network. Each receptor subtype typically has a different binding affinity for the given neurotransmitter. Therefore, the neurotransmitter may bind more strongly or more weakly to one subtype over another. This is most likely an effect of genetic variation, as the genes coding for the protein(s) present in the receptor slightly vary from subtype to subtype, yet still allow for binding by the neurotransmitter ligand.
A good analogy for the way in which a neurotransmitter binds to receptor sites is?
a key fitting in the lock of a door
What are holes in the surface of the dendrites or certain cells of the muscles and glands that are shaped to fit only certain neurotransmitters?
Neurotransmitter receptor sites on ligand-gated ion pores.
What determines whether a neurotransmitter will have an inhibitory excitatory effect?
How a neurotransmitter interacts with the receptors determines its effects. They activate receptors to perform specific functions in the body.the type of receptor
The same receptor can have different effects depending on the properties of the?
ligand that binds to it. For example, a receptor can trigger different signaling pathways or cellular responses if it binds to different ligands, even if they bind to the same binding site on the receptor. This is known as ligand-dependent receptor activation.
What does the neurotransmitter bind to after it moves across the synaptic cleft?
The neurotransmitter binds to specific receptors on the postsynaptic neuron's membrane. This binding triggers a series of events that can either excite or inhibit the postsynaptic neuron, ultimately influencing its activity.
Which neurotransmitter receptor is present on the sarcolemma?
Acetylcholine receptor is present on the sarcolemma of the muscle cells. This receptor is responsible for transmitting the signal to initiate muscle contraction when acetylcholine binds to it at the neuromuscular junction.
