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Atorvastatin was discovered in 1985 by Bruce Roth and colleagues at Warner-Lambert (now Pfizer). It was later approved for medical use in 1996.

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How atorvastatin crystalline differ from atorvastatin amorphous?

Atorvastatin crystalline forms have a defined molecular arrangement with a specific lattice structure, making them more stable and predictable in terms of properties and behavior. In contrast, atorvastatin amorphous lacks a defined structure, resulting in higher solubility and faster dissolution rates, but it is less stable and more prone to changes under different environmental conditions.


Why calcium carbonate added in a Atorvastatin calcium tablet?

Calcium carbonate is added to Atorvastatin calcium tablets as a buffering agent to help stabilize the pH of the tablet formulation. This helps ensure the drug remains stable and active throughout its shelf life. Additionally, calcium carbonate can aid in the absorption of Atorvastatin in the body.


Atorvastatin solubility in water?

Atorvastatin is slightly soluble in water, with a solubility of approximately 13.5 mg/L at 25°C. This low solubility can affect its bioavailability when taken orally. It is recommended to take atorvastatin with food to improve its absorption.


Does atovastatin contain sulphure?

Atorvastatin does not contain sulfur in its chemical structure. Its active ingredient is atorvastatin calcium, which is a synthetic compound primarily composed of carbon, hydrogen, nitrogen, and oxygen. If you have specific concerns about allergies or ingredients, it's always best to consult a healthcare professional or check the product's packaging.


What is the dissolution method for atorvastatin tablets if you want to analyze by uv spectroscopy?

the best conditions for atorvastatin calcium 10 mg tablets is as the following dissolution media is 0.05 potassium dihydrogen phosphate buffer PH is 6.8 use paddle II 75 rpm for 45 min make standard dilution in the same media and max abs. is almost at 243 nm for higher conc of atorvastatin use sodium lauryl sulphate 0.5 %

Related Questions

What is the ingredients in atorvastatin?

Atorvastatin calcium.


How many mg of atorvastatin calcium equivalent to atorvastatin 10mg?

Atorvastatin calcium is the salt form of atorvastatin, and the conversion is not a direct 1:1 ratio due to differences in molecular weight. For atorvastatin, the typical conversion is approximately 1.2 times the dosage of atorvastatin when expressed as atorvastatin calcium. Therefore, 10 mg of atorvastatin corresponds to roughly 12 mg of atorvastatin calcium. Always consult with a healthcare professional for precise dosing information.


What drug is generic atorvastatin?

The generic drug Atorvastatin goes by the brand name Lipitor.


What Medications that cause teeth grinding?

atorvastatin


What are pyrrole ring containing drugs?

Atorvastatin


Can you take atorvastatin and famotidine together?

Yes, there is no problem in taking lipitor (atorvastatin) and pepcid (famotidine). There is no real interaction between those two drugs.


How atorvastatin crystalline differ from atorvastatin amorphous?

Atorvastatin crystalline forms have a defined molecular arrangement with a specific lattice structure, making them more stable and predictable in terms of properties and behavior. In contrast, atorvastatin amorphous lacks a defined structure, resulting in higher solubility and faster dissolution rates, but it is less stable and more prone to changes under different environmental conditions.


What is the duration of atorvastatin and fenofibrate treatment?

up to 5years


Does atorvastatin and ramipril affect oral glucose tolerance tests?

no,not at all


Why calcium carbonate added in a Atorvastatin calcium tablet?

Calcium carbonate is added to Atorvastatin calcium tablets as a buffering agent to help stabilize the pH of the tablet formulation. This helps ensure the drug remains stable and active throughout its shelf life. Additionally, calcium carbonate can aid in the absorption of Atorvastatin in the body.


Is it safe to eat cutie oranges if you take atorvastatin?

Yes, it is generally safe to eat Cutie oranges while taking atorvastatin. There are no known interactions between atorvastatin and oranges or other citrus fruits that would pose a risk. However, it's always a good idea to consult your healthcare provider if you have any concerns about your diet while on medication.


What happens if you snort atorvastatin?

Snorting atorvastatin, a medication used to lower cholesterol, is dangerous and not recommended. It can lead to serious health risks, including damage to the nasal passages, respiratory issues, and potential overdose. Atorvastatin is designed to be taken orally, and misuse can hinder its effectiveness and cause harmful side effects. Always use medications as prescribed by a healthcare professional.