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Phosphofructokinase (PFK)

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KAMRAN

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What is used up during the first step of glycolysis?

Two molecules of ATP are consumed during the first step of glycolysis, where glucose is converted to glucose-6-phosphate by the enzyme hexokinase.


What is a rate-limiting enzyme?

A rate-limiting enzyme is an enzyme that catalyzes a crucial step in a metabolic pathway and determines the overall rate of that pathway. It usually operates at a slower pace compared to other enzymes in the same pathway, making it the bottleneck for the flow of metabolites. By regulating the activity of this enzyme, cells can control the production of various end products, ensuring metabolic balance and efficiency. Examples include HMG-CoA reductase in cholesterol synthesis and phosphofructokinase in glycolysis.


What is the function of aldolase in regulation of glycolysis?

Aldolase catalyzes the cleavage of fructose 1,6-bisphosphate into glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in glycolysis. This step is irreversible and serves as a regulatory point in glycolysis, controlling the flow of metabolites through the pathway.


What are example of enzymes regulated by feed back?

Glucokinase is the enzyme responsible for phosphorylation of glucose in the first step of glycolysis. The glucokinase complex is modified by two different molecules: citrate and ATP. Citrate and ATP are both products of the sequence of reactions in aerobic respiration and are consequently products of glycolysis. As these two molecules' concentrations in the cell build up, they bind to the allosteric site of glucokinase and shut it down.


What catalyzes each step of the pathway?

Various enzymes catalyze each step of a metabolic pathway. Enzymes are biological catalysts that speed up chemical reactions in living organisms. Each step of a pathway requires a specific enzyme to facilitate the conversion of substrates into products.

Related Questions

Which of the following enzymes catalyzes an unfavorable step in glycolysis?

Hexokinase


Which of the following enzymes catalyzes the rate-limiting step of glycolysis?

Phosphofructokinase


What is the control point in glycolysis?

The control point in glycolysis is the enzyme phosphofructokinase. This enzyme catalyzes the conversion of fructose 6-phosphate to fructose 1,6-bisphosphate, a key step in the glycolysis pathway. Phosphofructokinase activity is allosterically regulated by ATP, citrate, and AMP levels in the cell.


What reaction does the enzyme hexokinase catalyze?

Hexokinase catalyzes the phosphorylation of glucose to glucose-6-phosphate using ATP as a phosphate donor. This reaction is the first step in glycolysis and plays a crucial role in glucose metabolism in cells.


The enzyme hexokinase catalyzes the first step of glycolysis, and is crucial to initiating the process and preventing the initial substrate from easily traveling out of the cell (as its pre-reaction structure is membrane permeable)?

Glucose, glucose-6-phosphate


What substrate is converted into glucose 6 phosphate by the enzyme hexokinase?

Glucose is the substrate that is converted into glucose 6-phosphate by the enzyme hexokinase. Hexokinase catalyzes the phosphorylation of glucose to glucose 6-phosphate in the first step of glycolysis.


Why Hexokinase phosphorylated the glucose at first step of glycolysis?

The first step in glycolysis is catalyzed by hexokinase, an enzyme with broad specificity that catalyzes the phosphorylation of six-carbon sugars. Hexokinase phosphorylates glucose using ATP as the source of the phosphate, producing glucose-6-phosphate, a more reactive form of glucose.


What is used up during the first step of glycolysis?

Two molecules of ATP are consumed during the first step of glycolysis, where glucose is converted to glucose-6-phosphate by the enzyme hexokinase.


What limiting enzyme in the Krebs cycle is?

Isocitrate dehydrogenase is a key limiting enzyme in the Krebs cycle. It catalyzes the conversion of isocitrate to alpha-ketoglutarate, a critical step in the cycle.


What molecule is the reactant in the first reaction of glycolysis?

http://wiki.answers.com/Q/What_molecule_is_the_reactant_in_the_first_reaction_of_glycolysis"


What step in glycolysis consists of a phosphorylation reaction in which ATP is the phosphate source?

The sixth step of glycolysis, which involves the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate, consists of a phosphorylation reaction where ATP is used as the phosphate source. This step is catalyzed by the enzyme phosphofructokinase-1.


What is hexokinase?

Hexokinase is an enzyme that catalyzes the first step in glucose metabolism by phosphorylating glucose to form glucose-6-phosphate. This enzyme plays a crucial role in maintaining glucose homeostasis and energy production in cells. There are different isoforms of hexokinase that are found in various tissues, each with specific functions and regulatory properties.