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Which source of nicotinic acid C6H5NO2 from a nutritional view is best for use in a multivitamin tablet?
Niacin has is not only needed by the body for healthy skin caring for the nervous system an more but has also been prescribed for its effectiveness at lowering LDL and raising HDL cholesterol levels (Niacin acts in the breakdown of all major foods). With so many sources available for niacin the question arises whether a natural source or chemically manufactured one better for the body. There has been much debate to answer this question; however, to receive the most from your vitamin supplement the healthier choice is the natural choice.
It has been shown to be more economical to produce vitamin supplements from chemical sources yet as Dr. Jenkins stated in one study "there are no natural food components in most USP (United States Pharmacopoeia) vitamin formulas (Diet Factors Affecting Nutrient Absorption and Metabolism)". The method that the body employs to receive nutrients is partially dependant on their interaction with each other and the natural sources provide for this interaction with greater ease. One study provided that "niacinamide is 3.94 times more absorbed in the blood than USP niacinamide and 1.7 times more retained in the liver than isolated USP niacinamide (Bose)". As a secondary to natural vitamins the body receives co-factors such as, for example, "carrot powder contains bioflavonoid like beta carotene which is a precursor to Vitamin A" (Agrawal). The downside to synthesized vitamins is that do not contain the antioxidants found in natural vitamins (Agrawal).
Works Cited
Agrawal, Kevin. Vitamin Supplements, Synthetic or Natural. 7 Feb 2010
Bose, Vinson J. et al. "Bioavailability Studies." Nutrient Availability: Chemical and Biological Aspects 1989: 125-127.
Jenkins, DJA and TMS Wolever. "Diet Factors Affecting Nutrient Absorption and Metabolism." Modern Nutrition in Health and Disease 1994: 583-602.
Niacin acts in the breakdown of all major foods. 5 Feb 2010
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