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In the current model of cancer development, namely the initiaion-promotion-progression model, cancer development is presumed to be a very time-consuming process. The process of initiation, which is the process of rendering a single cell susceptible to developing into a malignancy, can take mere milliseconds to seconds, usually with the damage of DNA with chemicals or radiation followed by a round of cell division before the damage can be repaired. The initiated cell then needs to be promoted under the right circumstances. If the circumstances are not available, the initiated cell can lay dormant until it is promoted or until it dies. A promotion event always involves the selective amplification of the initiated cell population. The promoted cell can then divide and proliferate and progression begins. During progression, the body will try to either 'remodel' the promoted cells to try to make them behave normally again or kill them via the immune system. Progression is by far the longest of the phases and can stretch for years to decades. The body will initially gain an upper hand and may succeed in destroying the promoted cells. However, as the body ages, various mechanisms involved in remodeling and killing these cells become less efficient and the promoted cells may proliferate beyond the body's control, gaining mutations and eventually form a tumor. Therefore, in general, age is almost a prerequisite for people without congenital defects to get cancer since the normal process of progression takes decades. The body's defensive machinary becomes less and less efficient at stopping the pre-cancer cells as the body ages.

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The likelihood of getting cancer increases by?

It increases a lot...... if a family member has had it.... not like a grandma but a parent or sibling. If you are overweight. People need to eat plenty of vegetables seriously they vitaminsetc can reduce your risk of cancer considerably. You have to eat healthy.. but not over the top. Also some foods can seriously increase the risks. They say breast feeding can reduce the risk of cancer well obveously it doesnt because those who have breast fed have contracted the disease. As you get older as well your risk of getting cancer hugely increases, an unbelieveable amount if people are diagnosed with cancer every year. Personaly i dont think there is anything we can do.


X-rays damage DNA in organisms Rosalind Franklin died of cancer at an early age How might her work with X-ray diffraction have led to her death?

Rosalind Franklin's work with X-ray diffraction involved exposure to high levels of radiation, which can damage DNA and increase the risk of cancer. This prolonged exposure to X-rays likely contributed to her development of cancer at an early age.


If you have a brother or a sister with Down syndrome does this increase the chances of giving birth to a child with Down syndrome?

Having a sibling with Down syndrome does not directly increase the chances of giving birth to a child with Down syndrome. The risk is influenced by maternal age, not family history. If both parents are carriers of the genetic translocation for Down syndrome, the risk may be higher.


Does water increase with age?

No, water does not increase with age. Our body's water content may fluctuate based on factors like hydration status and muscle mass, but overall the total amount of water in the body does not increase with age.


What did Gene Upshaw die from?

Gene Upshaw died from pancreatic cancer in 2008 at the age of 63.

Related Questions

What is the average age of breast cancer victims?

Almost all breast cancer cases are after age 30-35. The chance of getting breast cancer in a lifetime is 1/8, the chances before 35 is 1/400, the chance before 25 is like 1/20,000.


What can increase someones chance of getting cancer?

smoking genetic pre disposition poor diet old age


What is minimum age a woman can suspect breast cancer?

The chances increase dramatically with age. Breast cancer is virtually unheard of before age 20 and extremely rare before 25.


Can you get breast cancer at age 12?

I can't say it's impossible, but it's certainly not worth worrying about. The chances of getting it are almost nil (0).


What is the chance someone will get benign prostatic hyperplasia?

The chances someone will get benign prostatic hyperplasia depends on their age. under 40 the chances are about 1 in 12. as you get older the chances increase to about 50%. then after 80 years of age the chances are about 80%.


Why does cancer risk increase as you age?

as you age your immune system becomes weak this may be the reason


Can a14 year old get testicular cancer?

I'm not sure but if you have hit puberty then it's possible i suppose but unlikely. it is the same with teenage girls getting breats cancer- its possible but very unlikely at such a young age. i hope this has helped you..... however if you did feel a lump chances are it could just be growth tissue at your age.


What is the chance of getting third age amour on runescape?

Chances are : 1/10,000


What are the chances of getting pregnant by IUI at the age of 25 with no infertility problems?

1


Who gets breast cancer?

There are several risk factors that increase the chance of breast cancer, however it is not known what the exact causes are. Some of the common causes are:Age and gender - Over a period of time, the chances of developing breast cancer increasesFamily history of breast cancerGenesMenstrual cycle - Women got their periods early (before age 12) or went through menopause late (after age 55) have an increased risk for breast cancerChildbirth -Women who give birth after the age of 30 are more likely to develop breast cancerAlcohol use - Consuming more than 1-2 glasses increases your chances of breast cancer


Does the age of a mother increase the chances of having offspring with a genetic disease?

There is an increase in the chance of for instance, Downs syndrome as the mother gets older.


What is the chances of getting 3rd age from a clue in runescape?

Approx. 1 in 10,000 or .0001%