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During George Washington's presidency, the primary leaders who disagreed and formed the first political parties were Alexander Hamilton and Thomas Jefferson. Hamilton, as the Secretary of the Treasury, advocated for a strong central government and a national bank, while Jefferson, the Secretary of State, favored states' rights and agrarian interests. Their conflicting visions for the nation led to the emergence of the Federalist Party, which supported Hamilton's ideas, and the Democratic-Republican Party, aligned with Jefferson's beliefs. This ideological divide laid the groundwork for the U.S. political party system.

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