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Cystic Fibrosis
An inherited disease affecting exocrine glands and resulting in chronic infections in the respiratory system and faulty pancreatic function.
454 Questions
Does Cystic Fibrosis effect Reproduction?
Yes it can, the thick and viscous mucus can block the sperm ducts for example and can therefore lead to sterility, as the sperm cannot be released.
Is cystic fibrosis a comunicable or non comunicable disease?
cystic fibrosis is a Genetic disease and in the case of cystic fibrosis, it's not affected others by any external medium like air , water etc that mean it's not a communicable disease.
Why does cystic fibrosis shorten life spand?
Unfortuently they die from the comboe of lack of nuitrients and because of all the mucus build up in their lungs they get lung infections and it'll eventually kill them. :( cystic fibrosis is a inherited diesas so dont get afraid of it. but anyways it dont just effect your lungs it also effect your digestive system. some people dont have it as bad so they can live into their 30s and 40s
Cystic-containing cysts.
Neoplasms-another word for tumor.
What is cause of residual fibrosis?
CF is a genetic disorder. In order for a child to have CF, 2 recessive alleles must be present. Only two CF carriers can produce offspring with CF, only there is a 25% chance that the offspring has CF. CF carriers DO NOT have CF, but have the gene that causes it (like birds that carry West Nile).
It's a genetic disease where patients affected have both of the two copies of the gene CFTR with mutation inactivating the gene. It brings to the formation of a CFTR protein with absent or decreased function. The CFTR is a transmembrane channel that transport chlorine ions (Cl-), so the patients affected have an abnormous concentration of Cl- on the mucose leadind to an increased viscosity of mucus that causes problems expecially at the lungs and pancreas, and to the reproductive apparatus. The average life of CF patients is very decreased. The gravity of the symptoms variate from patient to patient and it depends on the kind of mutations present, so there are severe forms, mild and light forms.
cystic fibrosis is an inherited disease which means you can only get the disorder passed on to you from your parents. However because the CF allele is recessive both parents have to be carriers and even then there is a 25% chance of inheritance
How dangerous is cystic fibrosis?
It can be very deadly.
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How many people died from cystic fibrosis in each year?
Deaths from Cystic Fibrosis: 485 deaths (NHLBI 1999)
Death rate extrapolations for USA for Cystic Fibrosis: 484 per year, 40 per month, 9 per week, 1 per day, 0 per hour, 0 per minute, 0 per second. Note: this extrapolation calculation uses the deaths statistic: 485 deaths (NHLBI 1999)
45 people died from cystic fibrosis in Australia 2000 (Australia's Health 2004, AIHW)
Source(s):RRTHow is a child born with cystic fibrosis?
Cystic fibrosis is genetic and is not contagious A person gets it when he/she inherits two mutated genes off each parent. A healthy couple can have a child with Cystic fibrosis because the parents would be carriers of the disease (even though they are unaffected by it themselves). 25% of children are at risk of the disease as it can be passed down from previous generations.
What body systems are affected by cystic fibrosis?
Cystic fibrosis affects the respiratory, digestive, and reproductive systems.
What is the long term prognosis for a cystic fibrosis sufferer?
The long-term prognosis for someone with cystic fibrosis varies greatly from person to person. Genetic mutations, modifier genes, environmental factors, and, to some degree, luck can all influence the progression of the disease. Many people with cystic fibrosis live into their 20s, 30s, and beyond but there are some that do not. There are exciting new drug therapies in the pipeline that have the ability to change cystic fibrosis from a life-shortening disease to a completely manageable disease. For instance, the drug Kalydeco is considered a functional cure for a certain subset of the CF population.
Can a genetic counselor use a karyotype to identify a carrier of cystic fibrosis why?
No, a karyotype looks at the physical structure of the chromosomes. Cystic fibrosis is caused by mutations in the CFTR gene. Karyotypes cannot identify a mutation at the base pair level, only large deletions, duplications, rearrangements of the chromosomes. It would be comparable to trying to use a magnifying glass to look at electrons.
What term describes the inheritance if cystic fibrosis?
The term that best describes the inheritance of cystic fibrosis is that it is genetic. Cystic fibrosis is caused by recessive alleles. Cystic fibrosis is an autosomal recessive genetic disease.
What is everyday life like for a person with cystic fibrosis?
It is usually pritty easily for those who are lucky and don't have it to bad except for all the treatments and medications. Most go around like normal unitl they have trouble breathing and then it feels like your lungs are filling with liquid and your body is drowing it's self. My boyfruend has CF so this information is coming directly from someoe who has it.
What is the genotype of an individual that is not affected with cystic fibrosis?
Let's call the gene "C." Capital C means no cystic fibrosis; lower c means cystic fibrosis, since it is a recessive gene. CC is a person who does not have cystic fibrosis and also is not a carrier. Cc indicated a carrier. cc shows a person with cystic fibrosis. In order for a child to have cystic fibrosis, its parents must be:
1. cc and cc (both have cystic fibrosis, so every child will as well.)
2. Cc and Cc (both carriers; 25% chance of having a child with cystic fibrosis)
3. Cc and cc (one parent is a carrier and one has cystic fibrosis; there is a 50% chance that the children will have cystic fibrosis.)
What are 3 emotional effects of cystic fibrosis?
In my experience with my long-term boyfriend (32 yo. CF patient), the biggest emotional effect I see with him having CF has been that since the time he was very little, he remembers feel different. As an adult this has turned into feelings of loneliness and being alone. It has had many serious implications on our relationship and other relationships he has had.
The lingula is a projection of the upper lobe of the left lung. Lingular fibrosis is scarring of the alveoli, or air sacs, in that location. There is no known cure for lung fibrosis.
Who famous people with cystic fibrosis?
Albert Einstein: Albert Einstein, one of the greatest scientists of the past better known for his theory of relativity and specifically mass-energy equivalence expressed by the equation E=mc2, died of internal bleeding caused by the rupture of an aortic aneurysm in Princeton's hospital, New Jersey, on April 18, 1955 at the age of 76, and is thought to have suffered from cystic fibrosis.
The treament for Cystic Fibrosis is?
Cystic fibrosis currently does not have any sort of cure. Treatment is mainly done to reduce symptoms and complications. Treatment options include antibiotics, mucus-thinning drugs, and oral pancreas enzymes.
Is cystic fibrosis preventable?
No, this is an inherited disease. If you are concerned about having a child with cf you can get genetic testing to see if you and your partner are carriers of the gene.
If you and your partner are carriers - 25% chance
If one of you has CF and the other is a carrier - 50% chance
If you both have CF - baby will have CF
If neither partner is a carrier - 0% chance
What is the risk in each pregnancy of having a child with cystic fibrosis?
By "another pregnancy", I assume that the parents have had one child with cystic fibrosis. As cystic fibrosis is recessive and neither parent suffers from it, they must both be carriers. That means the chances of the next baby having CF is 25%, or a one in four chance. Assuming both parents have one CF and one non-CF gene, the combinations work out: non-CF x non-CF (normal) non-CF x CF (carrier) CF x non-CF (carrier) CF x CF (cystic fibrosis sufferer) Therefore their chances of having a: normal child = 25% child who is a CF carrier = 50% child who suffers from CF = 25%
What animals get cystic fibrosis?
Yes I believe they can. Ihave just had to put my 7 year old dach. to sleep for what looked like pulmonary edemia. He had been having recurent lung infections for over 3 years, We tested him for allergies,etc. and nothing ever came up. We did chest xrays, blood work ,ultrasound and still nothing He acted like he had asthma and would get better then worse and over the years with treatment, he eventually started to gurgle. At the end he was on 10 pills in am and pm, valium,codien, and two inhalers,I looked in his eyes and he told me he was tired and I knew I could not keep him going like this it was not the life he wanted. When the veterinary did a autopsy his lung were filled with a thick stringy mucus. His lungs looked to have multiple abcesses filled with this mucus. This is the only finding so far ,but as anurse this sounds and in hindsight looked like cystic fibrosis. Only time and the pathology report will tell the truth if dog can get cystic Fibrosis
How can genetic engineering improve cystic fibrosis?
They isolated functional CFTR gene. Then they inserted the CFTR gene into nondisease-causing adenovirus virus. Last, they infected the patient´s airway cells with virus carryinhg the healthy CFTR gene.
