Cystic Fibrosis

By studying the families pedigree chart

Postural Drainage.

Copied and edited from someone else's answer on a similar question (they're not registered on WikiAnswers or I'd reference them): They form because the water from their sweat evaporates and then the salt can't go with it! You might like to check the other questions regarding salt and cystic fibrosis as I don't think the above answer quite covers your question.

Good Question. The answer is cystic fibrosis is not contagious, however, people with cystic fibrosis tend to carry bacterial infections that can cause serious issues to other people with CF, so infection control procedures should be used when two or more cystics are around each other. General population folks need not fear of getting cystic fibrosis from others - it's a hereditary disease.

Dr. Paul Quinton, who has CF himself, discovered that the basic defect in the CF sweat duct was due to anion impermeability and not defective anion exchange. His discovery is considered to be one of the major advances in understanding the basic CF defect.

Cystic fibrosis is an inherited chronic disease that affects the lungs and digestive system of about 30,000 children and adults in the United States (70,000 worldwide). http://www.cff.org/

CF develops early in childhood, the most common at 3 months. Simple genetic tests can tell you if you carry the gene that produces CF. CF is found in chromosome 7 and has 3 'ladder steps' missing. This results in the child having CF.

Some clinical manifestations include: chronic cough, pancreatic insufficiency, poor weight gain, repeated lung infections, salty tasting skin, and wheezing. There are many other symptoms and they vary considerably from person to person.

For a baby to be born with Cystic Fibrosis, both parents must be carriers of the faulty CF gene. Where both parents carry the faulty gene, each child has a one in four chance of having CF, a two in four chance of being a carrier and a one in four chance of not having any CF genes.

The thick mucus seen in the lungs and its counterpart in thickened secretions from the pancreas, an organ responsible for providing digestive juices which help break down food. These secretions block the movement of the digestive enzymes into the duodenum and result in irreversible damage to the pancreas, often with painful inflammation (pancreatitis). The lack of digestive enzymes leads to difficulty absorbing nutrients with their subsequent excretion in the faeces, a disorder known as malabsorption. Malabsorption leads to malnutrition and poor growth and development because of calorie loss. Individuals with CF also have difficulties absorbing the fat-soluble vitamins A, D, E, and K. In addition to the pancreas problems, people with cystic fibrosis experience more heartburn, intestinal blockage by intussusception, and constipation. Older individuals with CF may also develop distal intestinal obstruction syndrome when thickened faeces cause intestinal blockage.

Here is an excellent candidate to show the ability of the internet to take a mischevious rumour and start furiously blowing it up to a status approaching fact.

I have had this claim appear in a gullible student's essay, but I can find no evidence whatsoever being presented in favour of it.

Not "I don't believe the evidence", but rather "there is NO evidence".

So did Einstein have CF? Sure! As much as Shakespeare, Super Mario and Jesus did too.

Polygenic means influenced by multiple genes. Cystic fibrosis is a single gene disorder, in which a mutation occurs in one gene that specifies cystic fibrosis, in this case CFTR gene. There are thousands of possible mutations in this gene but the most common mutation is the deletion of one codon.

Most white Europeans do not get cystic fibrosis. There is, however, a greater occurence of the recessive gene responsible for cystic fibrosis in Caucasians and Ashkanezi Jews than other races.

There is no cure for CF, and most individuals with cystic fibrosis die young: many in their 20s and 30s from lung failure. However, with the continuous introduction of many new treatments, the life expectancy of a person with CF is increasing to ages as high as 40 or 50. Lung transplantation is often necessary as CF worsens.

Cystic Fibrosis can be permanently treated, but you can control it with daily breathing treatments and clapping treatments( make cupped hands and then pat yourself or the patient on the chest and in the back) which loosens the thick, sticky mucus in the lungs. Some CF patients need to take medicine. Young CF kids and teens should exercise as much as they can because it loosens the mucus.

Hope this helps ;)

There are an infinite number of medicines that CF patients may use, but only five are available exclusively for CF patients. Tobramycin, an antibiotic, comes in two forms, known and Tobi and Tobra. Tobi is inhaled through a nebulizer, while Tobra is given intravenously through a PICCline, peripheral IV, or port. Colistimethate is also an antibiotic given either inhaled or intravenously, and is called Colistin in both cases. Hypertonic saline is just what you think it is: saltwater. Often used in the 7% concentration, it is inhaled and the salt dries out the lung cells, forcing the body to concentrate more water to the lungs. In turn, the cells take in water to neutralize the effect of the salt, and the cilia in the lungs are able to move again. Pulmozyme is a geneticly enhanced drug that breaks down the DNA which makes mucus in the lungs so thick, so it is easier to cough up. Finally, aztreonam, better known as Cayston, just passed FDA approval last year, and is another inhaled antibiotic.

The sweat test is both the easiest and most accurate test for CF. In this test, a small amount of the drug pilocarpine is placed on the skin.

My fiance has cystic fibrosis and when planning our future, I couldn't imagine not having children and making our own family together. I continued research on the web and found that adoption may not be our only answer. Intracytoplasmic sperm injection (ICSI), is the newest form of in vitro fertilization specified for males who have CF. Here is the website: http://esiason.org/newsResourcesInfert.html It provides the research information and even costs. I hope this helps out!

Since CF is a genetic disease, the only way to prevent or cure it would be with gene therapy at an early age. Ideally, gene therapy could repair or replace the defective gene. Another option for treatment would be to give a person with CF the active form of the protein product that is scarce or missing. At present, neither gene therapy nor any other kind of treatment exists for the basic causes of cystic fibrosis, although several drug-based approaches are being investigated. In the meantime, the best that doctors can do is to ease the symptoms of cystic fibrosis or slow the progress of the disease so the patient's quality of life is improved. This is achieved by antibiotic therapy combined with treatments to clear the thick mucus from the lungs. The therapy is tailored to the needs of each patient. For patients whose disease is very advanced, lung transplantation may be an option. CF was once always fatal in childhood. Better treatment methods developed over the past 20 years have increased the average lifespan of CF patients to nearly 30 years. These treatment approaches are detailed more fully below: * Management of lung problems *: A major focus of cystic fibrosis treatment is the obstructed breathing that causes frequent lung infections. Physical therapy, exercise, and medications are used to reduce the mucus blockage of the lung's airways. *: Chest therapy consists of bronchial, or postural, drainage, which is done by placing the patient in a position that allows drainage of the mucus from the lungs. At the same time, the chest or back is clapped (percussed) and vibrated to dislodge the mucus and help it move out of the airways. This process is repeated over different parts of the chest and back to loosen the mucus in different areas of each lung. This procedure has to be done for children by family members but older patients can learn to do it by themselves. Mechanical aids that help chest physical therapy are available commercially. Exercise also helps to loosen the mucus, stimulate coughing to clear the mucus, and improve the patient's overall physical condition. *: Medications used to help breathing are often aerosolized (misted) and can be inhaled. These medicines include bronchodilators (which widen the breathing tubes), mucolytics (which thin the mucus), and decongestants (which reduce swelling of the membranes of the breathing tubes). A recent advance, approved by the Food and Drug Administration, is an inhaled aerosolized enzyme that thins the mucus by digesting the cellular material trapped in it. Antibiotics to fight lung infections also are used and may be taken orally or in aerosol form, or by injection into a vein. * Management of digestive problems *: The digestive problems in CF are less serious and more easily managed than those in the lungs. A well-balanced, high-caloric diet, low in fat and high in protein, and pancreatic enzymes (which help digestion) are often prescribed. Supplements of vitamins A, D, E, and K are given to ensure good nutrition. Enemas and mucolytic agents are used to treat intestinal obstructions (hoped i helpedout) *: http://www.healthnewsflash.com/conditions/cystic_fibrosis.php Since CF is a genetic disease, the only way to prevent or cure it would be with gene therapy at an early age. Ideally, gene therapy could repair or replace the defective gene. Another option for treatment would be to give a person with CF the active form of the protein product that is scarce or missing. At present, neither gene therapy nor any other kind of treatment exists for the basic causes of cystic fibrosis, although several drug-based approaches are being investigated. In the meantime, the best that doctors can do is to ease the symptoms of cystic fibrosis or slow the progress of the disease so the patient's quality of life is improved. This is achieved by antibiotic therapy combined with treatments to clear the thick mucus from the lungs. The therapy is tailored to the needs of each patient. For patients whose disease is very advanced, lung transplantation may be an option. CF was once always fatal in childhood. Better treatment methods developed over the past 20 years have increased the average lifespan of CF patients to nearly 30 years. These treatment approaches are detailed more fully below: * Management of lung problems *: A major focus of cystic fibrosis treatment is the obstructed breathing that causes frequent lung infections. Physical therapy, exercise, and medications are used to reduce the mucus blockage of the lung's airways. *: Chest therapy consists of bronchial, or postural, drainage, which is done by placing the patient in a position that allows drainage of the mucus from the lungs. At the same time, the chest or back is clapped (percussed) and vibrated to dislodge the mucus and help it move out of the airways. This process is repeated over different parts of the chest and back to loosen the mucus in different areas of each lung. This procedure has to be done for children by family members but older patients can learn to do it by themselves. Mechanical aids that help chest physical therapy are available commercially. Exercise also helps to loosen the mucus, stimulate coughing to clear the mucus, and improve the patient's overall physical condition. *: Medications used to help breathing are often aerosolized (misted) and can be inhaled. These medicines include bronchodilators (which widen the breathing tubes), mucolytics (which thin the mucus), and decongestants (which reduce swelling of the membranes of the breathing tubes). A recent advance, approved by the Food and Drug Administration, is an inhaled aerosolized enzyme that thins the mucus by digesting the cellular material trapped in it. Antibiotics to fight lung infections also are used and may be taken orally or in aerosol form, or by injection into a vein. * Management of digestive problems *: The digestive problems in CF are less serious and more easily managed than those in the lungs. A well-balanced, high-caloric diet, low in fat and high in protein, and pancreatic enzymes (which help digestion) are often prescribed. Supplements of vitamins A, D, E, and K are given to ensure good nutrition. Enemas and mucolytic agents are used to treat intestinal obstructions (hoped i helpedout) *: http://www.healthnewsflash.com/conditions/cystic_fibrosis.php

Yes, cystic fibrosis is an autosomal recessive disease.

this is so false, no he did not

Vanessa and Miley bonded while Miley visited her at a hospital in LA. Apparently they became very close. Then Vanessa unfortunately passed away in 2007. Miley still does work with the Cystic Fibrosis Foundation.

Yes, it is a genetic, inherited disease where a child must receive 2 alleles for cystic fibrosis in order to exhibit symptoms. If a child only receives one of the recessive alleles, they are known as a carrier because they have the ability to pass that gene on to their children.