No. Of course not.
the fentanyl is much stronger@ 400mcg,dont eat these things unless your opiate tolerant.there prescriped for cancer patients
You can't - the only thing you'll do by increasing the delivery rate is subject yourself to an overdose if you're not careful.
If you want to cut down on the drop off between the last patch and a new one, put the new one on 6 hours before the one you have on is supposed to wear off. Over time you'll know when it's supposed to wear off.
Yes, it is done everyday. Pain patients may have the Duragesic patch and also have emergency oxycodone tablets up to 30mg. However, these people have a largely developed tolerance to the opiate drugs. I would not recommend doing it unless you have a very large tolerance. Hope this answers your question. Stay safe!
-Patrick (Future Pharmacological tech)
It depends on your overall condition, reason for pain, your overall tolerance level, and the length of time you've been using Fentanyl Transdermal patches of any type. However, in general, if you're up to the task, then yes, it's okay, as long as you're aware of the potential risks involved.
Fentanyl patches (either Duragesic or its generic alternatives) work by slowly releasing the drug through a transdermal membrane into the bloodstream via the skin layer. The dosage delivery is controlled by body heat, and naturally any strenuous physical activity will increase your heart rate and elevate your core body temperature. This alone increases the dosage delivery rate, and if you're not yet that tolerant to the drug or opiates in general (rare since the patches are only supposed to be prescribed to prior opiate tolerant patients), then confusion or other increased side effects can occur.
As a long time Duragesic user and chronic pain patient on opiate therapy for many years (see my bio for specifics), I've experienced this several times while doing outside work or remodeling around my home. Even though I knew what was happening, the confusion level is so much that it's difficult to get out of the situation on your own. I describe it as being stuck in a loop you can't get yourself out of. Only removing the patch (if you do it properly you can re-attach it later - see my answer on that) or cooling your body to normal will alleviate the problem. It's also important to understand that opiates are Vasodilators, meaning they open the blood vessels (that's why you feel cold when the dosage tapers off - they start constricting). Opening the blood vessels wider naturally warms your body, but again if you're tolerant to the constant dosage over time then your body is already used to it.
However, if you take simple precautions to keep yourself from getting overheated (stay hydrated and cool while working) and your overall physical condition doesn't limit you from the work (e.g., you're dealing with extreme pain but are physically able to work), and you're prepared for what can happen (my family knows what to do if they find me in such a situation, and I always have my cell with me when working) then there isn't much you can't normally do that you didn't do before.
As you become more tolerant, the depressant effects will become less. I found years ago that a cerebral stimulant will help overcome the depressant effects to the point where I feel relatively normal. Of course I don't use them often, only when I'm using higher opiate dosages to control pain.
As far as driving, it's an individual situation. Not everyone handles opiate therapy the same way, and again only tolerant individuals can deal with the depressant side effects over time. I've never had any driving restrictions, though I've always been acutely aware that in any accident it would likely be an issue. Having said that, unless I told you that I was a high level opiate patient you'd never know as I feel normal most of the time. It's really a topic for your pain specialist and yourself, but if you've already got handicap driver plates or a placard, then your doctor has already signed off on the fact that he/she believes that you're okay to drive. How responsible you are is totally up to you. I won't drive if I need to increase my normal dosages to deal with increased pain.
You should also be aware of the fact that the patches will and do slow your reaction time, so you need to be more aware of safety factors and compensate for your slower reaction than normal when working. Also, remember that opiates work by altering the brain's perception of pain, and if you over-exert yourself, you could further aggravate your condition without realizing it until the pain becomes worse. Be smart.
If you're wondering, at my highest dosages I was using 2 100mcg Duragesic patches for primary pain, Percocet 10/325's for breakthrough (120/150 per month), 100mg Demerol tabs, and 30mg MS Contin tabs for pain. My normal dosages are 1 100mcg patch and the same amount of Percocet monthly. Those have been my normal dosages for about 9 years.
It depends on the person and the amount of gel involved. If you're extremely tolerant to Fentanyl, you won't be affected as quickly, but for most people, respiratory / cardiac arrest and death are the most common results. It's slower than Cyanide, but the end result is the same.
Fentanyl patches are designed to deliver a continuous, small dose over a period of 2-3 days. By removing the gel and applying it directly to the skin, the person is bypassing the timed-release component. Most people, high dose Fentanyl users as well, aren't capable of handling that high a dose at one time.
You can, but they are typically not prescribed together since they perform the same function - long term dosage delivery of opiate for chronic pain. They can be prescribed together when the patient is making the transition from OxyContin to Duragesic or vice-versa, but there's really no reason for it. All Duragesic patches come with information instructing the patient and doctor on the minimum starting dosage with a morphine equivalence chart that allows them to estimate your current equivalence with the drug you're using to the equivalent Duragesic dosage. Janssen Pharmaceuticals does skew the dosage estimates lower than they normally should be though for safety reasons, since all patients should start at the lowest dose and then work up to maintenance levels.
The difference is in the time factor - OxyContin has an advertised dosage time of 12 hours effective dosage, while Fentanyl patches are good for either 48 to 72 hours depending on the individual. For most people it's 72 hours, but a small percentage of the population (myself included) only gets 48 hours.
Since they're both controlled delivery drugs, Fentanyl patches are often prescribed when OxyContin tolerance has lowered to the point where the patient is only getting relief for about the same time that an acute pain medication does - just over 6 hours. Before I started using Duragesic, I was barely getting 7 hours out of OxyContin. The idea in pain management is to maintain a controlled dosage with less medication at a steady rate over long periods so that the patient doesn't have to rely on more medication to achieve the same results. Of course as tolerance increases, dosages may have to be adjusted, or increased if the pain increases. I've had to do this several times over the many years I've used Duragesic, but ultimately was able to return to my normal dosage levels after the reason for increased need was dealt with.
the fentanyl patch is a long timed system patch in which it lasts up to 72 hours per patch and dosage in your system compared to the tablet of Oxycontin in which it only lasts about 6-8 hours per pill depending on dose and your tolerance of pain medications
it ether means you have been hitting the bong pipes and stuff or that test is srewed up!
The amount of time it takes for the amount of drug in the body to reduce by 50% is called the half-life. It takes approximately five to six half lives for the drug to be cleared from the body. The half-life for fentanyl patches is 9.5 to 12.4 hours. Multiply that by 6 and it could take up to 74.4 hours to clear the drug. You can do the math. Fentanyl lozenges-approx. 7 hours.
Duragesic takes a few hours to kick in and is supposed to last up to 72 hours (like how Oxycontin is supposed to last 12 hours) but most people find it lasts 36-60 hours. From my experience I've found fentanyl patches to last about 48-54 hours. In regards to drug testing, assuming it's a UA, fentanyl takes longer to clear than most opiates, it would take AT LEAST 48 hours after the removal of the patch (assuming you wore it for at least 2 days)
The lethal dose is estimated to be between 1.25mg-2mg.
As a registered nurse who has been on Fentanyl dermal patches, after 2 major unsuccessful spinal fusions surgeries, I realized the scarring and normal arthritic changes over some years, can actually diminish our acute or even chronic spinal pain. That includes the radiation of pain down their spinal nerves, causing anterior (top to side) pain in your legs. Also, this can happen with upper cervical, thoracic and as in my case, thoracolumbar pain. The patches were a life saver for 20 almost 21 years. I was able to improve my exercise tolerance, increase going to family functions. Most importantly as you who are in the same boat know, there is a certain amount of guilt, when you feel, you can not make future plans, with family & friends, since one never knows, exactly how severe the pain will impede your activities of daily living. Therefore, I decided, I would with my physician's help and both our knowledge of pain management, try to totally withdraw from the application of these very expensive & sometimes, dangerous methods of chronic Opioid tolerant pain management. As a nurse, I feel compelled to make this statement. Using the Fentanyl systems of pain managment, can and have, been implicated in patients' deaths. There are many causes but the most common one believed, is due to diminished respiration, failure to breath well enough to oxygenate our bodies, improper application, duplicate application of patches if one does not write down, the placement on your body, the time and day it was applied, or by other errors. Heat increases the medication to coarse through our bodies. If you have a fever, or are too warm, pay much closer attention to your breathing. Never use alcohol to clean the patch site, again, rubbing or any alcohol, will increase the amount of drug in your system and can potentially cause, hypoventilation or complete cessation of breathing completely. This of course will be disastrous. The more senior you are the more, one needs to consider every aspect of your overall health. I'm right up there folks, in my 60's. That's why I wanted to answer this question with my own experience.
I personally am decreasing my Fentanyl patch dosage, in what I feel is a safe manor. I was able to decrease my dosage from Feb.6th through the end of March, (2 months) from 100 micrograms, down to 50mcg. During this decrease, whether from personal issues in my family, with several deaths of younger family due to accidents, or as a result of the decrease in the Fentanyl, I became morbidly depressed. Signs included, decrease in my physical activity. I needed to force myself to eat and drink properly with concomitant weight loss. I cried at the drop of a hat. I lost interest in all the hobbies I loved, and generally was sad, just not my bubbly self.
I failed to mention one very important warning whether about Lexapro or Fentanyl use, I stopped even social drinking a glass of wine, when I began applying Fentanyl and of course I still won't drink and wouldn't on Lexapro, on or off Fentanyl. There is an increase in the drugs' effects which can be severe. So please? Do not drink alcohol or mix any other psychotripic medication while on both of these meds.
Additionally it need to be mentioned: from the day I applied my first Fentanyl patch, and over the past 20+ years, I keep thorough records of my Fentanyl patches and Lexapro. It's actually a very good idea, to keep an up to date chart, (on your person) when and how much medications you've taken on a daily basis. Fentanyl in particular, can be a bit difficult to remember, the date and time you applied this patch which is either prescribed, on a 72 (3 day) basis, and lately I've read, even every 48 hours (two day period). I continually read the package inserts each time I open a new box, there have been many changes in how to apply and use them. If you're smart, you will read the package inserts and if you do not understand something written, call your pharmacist or the company's patients telephone answer line, for any questions you may have. Both of these medications can be life savers and both can be dangerous if used improperly. Get to know your meds and how they work in your body. Again, I cannot emphasize enough do not drink alcohol. If you must take a sip for a family wedding, etc., simply put a little wine on your lips, but NEVER swallow enough to alter how you feel emotionally.
I'd like to share how important age is when using either of these type of meds. I'm sharing with you, I am now 60 years old and I am extremely careful how I "chart" my medications. Or have a family member chart them for you. I feel very proud of myself, that I have successfully decreased my Fentanyl medication by half over a twp month time frame. However, once I hit the 50 mcg. level, I tried to decrease my dosage down to 25 mcg every 3 days and went into withdrawal, and major depression. I realize it's taken me a while to get to the question's point, but here is my experience:
YES, I did take and I am still am taking Lexapro 5 mg twice a day. I've been on Lexapro since February which is now three and one-half months, without any untoward or negative symptoms, in conjunction with MY Fentanyl patches. I hope you will ask your doc and remember, they are working for you! Don't feel you can't call and ask you doctor, if you have any questions such as this one: Can I SAFELY take Lexapro anti-depressant, if I am also applying a very strong Opioid analog pain patch such as Fentanyl.
It does not on standard at home- there is no panel for it and has a different structure that most opiods, you would have to be tested with a specific fet test
Yes it does. It can make you tired and docile.
You will die! Get some help if this what you are using it for. I have chronic pain and use a fentanyl patch, Norco, methadone just to be able to walk. your an idiot if this is your intent. People like you make it hard for people like me to get these drugs from dr! Get help and please don't eat the patch !
A 50mcg (patch dosages are in Micrograms, not Milligrams) fentanyl patch is equivalent to approximately 200 mg/day of oral morphine.
Yes - in fact, it's not uncommon for Xanax and similar drugs to be prescribed to chronic pain patients, either as part of normal mental therapy or for easing withdrawal symptoms.
It depends on the patient - by instruction, the patch must be applied on the upper torso or upper extremities (arms). Most people tend to put them on their back or chest, but I learned early on that for the back you need someone to change them, and the chest/stomach area has both too much hair and the skin flexes too much with activity.
As a result, for many years I've worn them on my biceps - they're flat, the patches easy to put on them with one hand, and the skin doesn't flex very much there. When using 1 100mcg patch, I just switch arms when it's time to put a new one on. When I have to increase to 2 100mcg patches, I use both arms, but take one off a few hours before the other to clean it and let the skin breathe before putting on a new one and taking the other one off. That way your dosage doesn't drop much during the process, and if you feel breakthrough you can take a Percocet or whatever your breakthrough med is to cover it.
The key to keeping a patch on (see the link to my answer on that below) is to make sure the skin is clean and there's no hair present. The literature says not to use any Isopropyl alcohol - that's because it leaves a residue. Problem is, it's difficult to remove skin oil and dirt without it. To get around the problem, clean it with Iso, then rinse the area well to make sure any residue is washed off. Dry the skin well, then apply the patch. If there's a lot of hair or micro-hairs, you might need to shave it off as well. Before you put the patch on, hold it between your hands (still attached to the backing) for about a minute to soften the adhesive. Apply it, then put your hand over it for another minute to ensure the adhesive gets a good bond to the skin. You'll find it sticks pretty well after that.
YES YES YES, Is all I can say ! I have chewed these and wore these and IF
u take enough it WILL CAUSE confusion & Many other things !
Depends how much you chew OR do and what else is in your system
just the patch ONLY = YES it will CAUSE CONFUSION if taken to much
all I say Is :
BE VERY CAREFULL when using this medication, stronger then oxycontins as well,
I take both for my Pains, and so I am telling you the REAL TRUTH Here !
It's never a good idea to drink alcohol while on any narcotics. However, one glass of wine will not kill you. The most serious side effect being respiratory suppression or god forbid respiratory cessation.
Considering Fentanyl is a epidermal patch, which releases a dose of Fentanyl over a 72 hour period. in comparison HydroMorphone (Diluadid) is more potent, depending on which route you use(IV,oral,IM,intranasal). so in contrast 25mcg of Fentanyl is not very strong,(Compared to Diluadid). AND I"M ONLY 18 AND I KNOW THIS FROM EXPERIENCE!!!!
Side effects of using Fentanyl patches are pretty common. Mood swings (typical with most opiates), urination (you won't feel it until you're ready to bust), respiratory problems (if you're not tolerant to the drug - if it happens at all call your doctor immediately), euphoria for first time users (until you get used to it). 25mcg is a pretty low dose, but if you're not that tolerant, increased body heat can increase the dosage delivery to the bloodstream. In such cases it can lead to confusion - as a 200mcg patient myself, it's happened to me several times over the years. You literally feel like you're stuck in a loop you cannot get out of. If you ever feel this way, remove the patch immediately (you can put it back on - just don't let it get stuck to itself. See my answer on keeping patches applied). Opiates are Vasodilators, meaning they open the blood vessels wider. As long as your body heat is higher from exercise or moving around, the drug will continue to be delivered at a higher rate, and if you're not that tolerant it will affect you adversely. It is difficult to realize what is happening to you, harder still to do anything about it until your body heat returns to normal. You should alert family and friends about what to do if they find you in a confused state and it's apparent you're overheated. Tell them to get your patch off and get you cooled down. Fentanyl takes several hours before you'll feel any withdrawal symptoms at all, and you should be well recovered before then.
If you have specific questions about side effects you can email me at my WA email listed on my Supervisor bio page. After nearly 10 years, there aren't many side effects I haven't experienced from it.
Additionally, nausea can be a major problem. As a 300 mcg patient, I lost 40 lbs. in 3 months. Zofran helped, but Marinol worked best .
NEVER CUT A FENTANYL PAIN PATCH, the dose becomes totally unstable. It will leach out into the skin and your clothing. It remains active to various degrees and times. If you put on that piece of clothing and a new pain patch it can lead to respiratory failure and death. I know this first hand from the death of my dear son, 39 yrs. old, husband and a father to our 3 1/2 yrs. old grandson. PLEASE consult with your doctor at all times and make sure you understand what your doctor or the literature from the pharmacy has stated. It doesn't matter what you read on the Internet, PLEASE check with the live professionals. My son thought "cutting back the dose" meant he could cut the patch. Unfortunately he is not here today to tell you himself. DON'T CUT IT! Which much love and pain, his Mom.
All Duragesic users experience withdrawals on a regular basis - it's the nature of using them. However, you can avoid the minor withdrawals if you overlap your patch changes. It takes several hours after your patch expires (or it's removed) before you really start to feel it. Initially you'll just feel cold and clammy (opiates are Vasodilators, meaning they open the blood vessels - the reason you feel cold is because the blood vessels constrict)
Duragesic takes several hours to ramp up to full dosage delivery, and the same goes for when it's running out. Eventually you'll learn when the dosage is low enough that you'll start feeling the first signs of withdrawals - not really that strong, but enough to get your attention. Severe Fentanyl withdrawal is not a good time, so never let yourself get that low on your meds. Try to stretch your patches so that you've got one or two extras at the end of the month - I've always maintained an emergency 1 month supply just in case.
The trick to avoiding the withdrawals is to know when your current patch is winding down. If you add your new patch as the other one is winding down, you'll find that your dosage level remains fairly constant, as one is ramping up to full dosage while the other one is expiring. You can always use your breakthrough meds if you need to if the expiring patch is too low.
For a month. You shouldn't be smoking Marijuana!
If you are using Fentanyl legally, and have a current prescription, this should not be a concern. Just show proof of you current script with a picture ID and a notation will be attached to your tox screen to disregard this if it is within the therapeutic dosage parameters of your prescription.
This does not apply in some staes, and you will be charged with a DUI if there is an MVA involved and/or you have alcohol in your system as well.
even if you are using this in an illicit way, i belive that fentanyl only stays in your body for 8-24 hours, so after a day, i dont think it will show up on a swab test.
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