No, X is the only letter in the alphabet in which has never had a player in the NFL as the first letter of their last name.
Xu Xiaoliang is famous in China. He is a Chinese Basketball player who participated in the 1988 Olympics.
Xavier Nady
Xavi
Quentin McCracken Quilvio Veras
zimmerman zimere
There are currently only two players on the Manchester United roster whose name (first or last) begins with a K. Those players are Shinji Kagawa and Michael Keane.
Uljana Semjonova is a retired Russian basketball player. She was one of the leading woman's basketball players in the world.
Omar Vizquel, Orlando Cabrera and Octavio Dotel are three players whose names begin with O.
hagiai
yes
tom seaver
Neil Armstrong was the first person to walk on the moon. Arthur Ashe and Andre Agassi are famous tennis players. Muhammad Ali is a famous boxer.
From recollection there have been NO players whose name begins with a "E" in the 1990 -99 years
Winnona Ryder
Ugo Ehiogu