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You can go from Minneapolis/St. Paul to Boston via Chicago. Take the Empire Builder that leaves St. Paul at 7:50 am and arrives in Chicago at 3:55 pm. Transfer to the Lake Shore Limited that leaves Chicago at 9:00 pm and arrives in Boston at 9:10 pm the next day. For the return trip, the train leaves Boston at 11:55 am and arrives in Chicago at 9:45 am the next day. Connect to the Empire Builder leaving Chicago at 2:15 pm and arriving in St. Paul at 10:31 pm.

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