This question is overbroad. In the 7000 years of civilization in the Middle East, almost everything about society, culture, religion, technology, self-perception, government styles, etc. has changed. Please resubmit with a timeframe to narrow the answer.
Trade flourished
The events of the Bible are centered in the Middle East. However, there is mention made of parts of Italy and parts of Greece.
European exploration of the Middle East (study island)
A suicide bomber killed 240 U.S. Marines in Lebanon.
the term middle east means the middle of the east.
it is, obviously in the middle of the direction east.
can anyone name the cold war events in the order they occured
The Gunpowder Plot
911
none
suck my balls
the American revolution