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No, not on a general basis if the owner makes sure the cat's shots are up to date and is well fed along with water and has a physical by the vet once a year. The only problem would be Allergies and sometimes ring worm. If rabies shots are not given and your cat is outside there is a possibility of the cat contracting rabies, but it's rarer than you think. I've had cats almost all my life (even a few that came to my parents house for a hand out and not once did my brother and I ever suffer from a harmful disease.

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