Mean as a rattlesnake.
"Savanna" mean "savane"
I think you mean "scalene", or uneven in length.
unisexual mean having 1 sex only and bisexual mean having 2 sex unisexual mean hetrophrodite and bisexual mean hermaphrodite
I means someone is full of there slef and mean to others!
PFK Piešťany was created in 1912.
High levels of ATP inhibit PFK
PFK-1 is primarily regulated by allosteric effectors such as ATP, ADP, and AMP, which signal the energy status of the cell to control glycolysis. PFK-2 is regulated by hormones like insulin and glucagon, which modulate its activity through phosphorylation/dephosphorylation. Additionally, PFK-2 is also influenced by fructose-2,6-bisphosphate levels, which act as a potent activator of PFK-1.
Citrate acts as an inhibitor of phosphofructokinase (PFK), which is a key enzyme in glycolysis. When citrate levels are high, it indicates that the cell has sufficient energy and metabolic intermediates, leading to the inhibition of PFK to prevent excessive glucose breakdown. This regulatory mechanism helps maintain energy balance within the cell.
One can have the answer, when the league is completed for this year!
Phosphofructokinase (PFK)
Some abbreviations for enzymes involved in the breakdown of glucose are HK (hexokinase), GK (glucokinase), PFK (phosphofructokinase), PK (pyruvate kinase), and G6Pase (glucose-6-phosphatase).
No, it is not true. PEP, or phosphoenolpyruvate, is actually a substrate for phosphofructokinase (PFK), a key enzyme in glycolysis. PEP is converted to fructose-1,6-bisphosphate by PFK, which is an important step in the glycolytic pathway.
Phosphofructokinase-1 (PFK-1)
Loss of allosteric binding site for ATP on phosphofructokinase-1 (PFK-1)
Phosphofructokinase (PFK) is considered the pacemaker of respiration because it is a key regulatory enzyme in the glycolytic pathway, controlling the rate at which glucose is metabolized for energy production. It catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate, a critical step that determines the flow of carbon through glycolysis. PFK activity is tightly regulated by various metabolites, particularly ATP and AMP, which allows it to sense the energy status of the cell and adjust the rate of respiration accordingly. This responsiveness makes PFK a central point of control in cellular energy metabolism.
Phosphofructokinase 1 (PFK-1) increases during exercise primarily due to elevated levels of AMP and adenosine, which signal a higher demand for ATP in muscle cells. As exercise intensifies, the ATP supply diminishes and AMP accumulates, activating PFK-1 to enhance glycolysis and glucose metabolism. This increase allows for greater production of ATP from glucose, supporting the energy needs of working muscles. Additionally, reduced levels of ATP and increased levels of fructose-2,6-bisphosphate further stimulate PFK-1 activity during vigorous physical activity.