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4 and 4 and 6 and 8 equals 24 you can only use the numbers once and you cant use the same math symbol more than once?

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((4 + 4) x 6) - 8 = 24 4*(4+8-6) = 24
or
(8+4)*(6-4) = 24
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How many possible 4 digit combinations are possible without using the same number more than once?

5,040 Assuming that the combination uses ALL single digits from 0 to 9, then for the first digit you will be able to use all 10 numbers, for the second digit you will be able