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I'm not 100% sure about long term, I would guess your mood would return to normal once meds are stopped. while on it you need to be under the care of a pscyh In response to above post: I was the first person to be treated in Washington state with Interferon, and was retreated 10 years later with combo Interferon-Ribavirin therapy. After nearly dieing from the Ribavirin combo I have suffered from many debilitating side effects. I have just been told that my immune system has gone after my body like an autoimmune syndrome. It has attacked my bones, Thyroid and other systems. I have suffered from deep depression for over 12 years now. It's better then being dead, meds control pain and depression.

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Q: Are there possible long term mental health consequences associated with interferon - ribavirin combination therapy for hepatitis C?
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