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Aspirin is an acid with pKa of 3.5 is aspirin more absorbed in stomach where pH is 1 or in small intestine where pH is 6?
Wiki User
∙ 13y ago
Aspirin is absorbed from the stomach but most of it is absorbed from small intestines because of poor dissolution of acidic drug in stomach acid, high dissolution in intestinal contents, large surface area on intestines and good blood flow in intestines
Wiki User
∙ 13y ago
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Is aspirin absorbed in the stomach or intestines?
Aspirin is absorbed both in the stomach and the small intestine , for the former the cause lies beyond the fact that the gastric PH (1.5-2.5) is lower than the pka of aspirin (3.5) such that the ionization of aspirin is so much limited and the unionized and subsequently the lipophilicity of aspirin increases so that it's easily absorbed into the gastric mucosal cells. for the latter , aspirin absorption is due to the large absorptive surface area of the small intestine despite the fact that the intestinal PH is higher than the pka of aspirin , but still the surface area help absorption of the unionized fraction of aspirin.
Where in the digesitve system is absorption?
alcohol and aspirin are absorbed in the stomach, everything else is absorbed in the small intestine and excess water and vitamins k and b are absorbed in the large intestine.
Does aspirin dessolve?
yes. your stomach acids will dissolve the pill, and then the chemicals that make up the aspirin will be absorbed and stop the pain
Does aspirin dissolve in the stomach or small intestine?
Yes I am. After taking any medication for three to four days I develop cold and flu like symtoms. I now have an entry in my profile at the pharmacy to only dispense uncoated medication. They do and always have it available so others must have similar difficulties.
What substances are acitively absorbed in the stomach?
Aspirin and alcohol are two substances that are actively absorbed in the stomach.
What substances are actively absorb by the stomach?
Aspirin and alcohol are two substances that are actively absorbed in the stomach.
Can the formula of aspirin be changed to produce less irritation to stomach?
Aspirin is "acetylsalicylic acid". Changing the chemical, changes the action. What is commonly done, is to coat the aspirin with a compound that does not let the aspirin dissolve in the stomach. This is called an "enteric coating". This helps a lot with stomach upset from taking regular aspirin.
What is the difference between aspirin to buffered aspirin?
Buffered aspirin has an added buffering agent so that it is easier on the stomach.
Why would doctors recommend buffeting aspirin especially for those with a sensitive stomach?
The term is BUFFERED aspirin. Aspirin is an acid, and can cause stomach upset. Adding another substance to aspirin (a buffering material) can help counter the acid of the aspirin- and no tricky tummy.
What is the purpose of combining maalox with aspirin?
Maalox buffers the acidic effects on the stomach of the aspirin.
Would changing from Ibuprofen aspirin 325mg to aspirin 81mg Tylenol be better for your stomach?
yes it is
Is bayer chewable low dose baby aspirin buffered?
If it is buffered it will say on the label. Bayer makes a Low dose safety coated Aspirin that is buffered. (81mg) It has an enteric coating. The enteric safety coating is designed to allow the aspirin to pass through the stomach to the small intestine before dissolving.
