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Adenosine receptors stick through the neuron membrane, so that part of them are on the inside and part is on the outside of the cell. Now, when adenosine, a natural chemical in the body, attaches to the adenosine receptor it shifts the shape of the receptor, this shift reaches all the way to the part on the inside of the cell, and causes the receptor to release attached molecules called G-proteins. These g-proteins now float around the inside of the cell and have all sorts of effects, in this case, to inhibit the neuron. Caffeine also binds to the adenosine receptor, but it doesn't activate the receptor. This means that the receptor is totally shut down, and can't work to inhibit the neuron any more. The end effect is to allow the neuron to be more active than it was before the caffeine.

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Q: How would caffeine binding to an adenosine receptor affect the activity inside the neuron?
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