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1. Resting potential: all voltage-gates are closed. 2. At threshold, Sodium activation gate opens and Sodium permeability rises.
3. Sodium enters the cell (influx), causing an explosive depolarization to +30 mV, which generation the rising phase of action potential.
4. At peak of action potential, sodium activation gate closes and sodium permeability falls, which reduces the net movement of sodium into the cell. At the same time potassium activation gate opens and potassium permeability rises. .
5. Potassium leaves the cell (efflux), causing the repolarization to resting potential, which generates the falling phase of action potential.
6. On return to resting potential, sodium activation gates closes and inactivation gates opens, resetting channel for another depolarizing triggering event.
7. Further outward movement of potassium through still open potassium channels briefly hyperpolarize membrane,
8. Potassium activation gate closes and membrane returns to resting potential
Wiki User
∙ 13y ago
Wiki User
∙ 9y agoThere are 8 steps in the action of potential. They are resting potential, the sodium activates and opens, sodium enters the cell, sodium activation gate closes, potassium leaves the cell, sodium activation gates close, potassium moves further, and the potassium activation gate closes.
Wiki User
∙ 14y agoAs sodium ions diffuse inward, the membrane loses its negative electrical charge and becomes depolarized. At almost the same time, however, membrane channels open that allow potassium ions to pass through, and as these positive ions diffuse outward, the inside of the membrane becomes negatively charge once more. This, the membrane returns to the resting potential (becomes repolarized), and it remains in this state until stimulated again.
This rapid sequence of depolarization and repolarization, which takes about one-thousandth of a second, is called action potential.
Source, page 212 unit3 of the Hole's Essentials of Human Anatomy and Physiology.
Published by McGraw-Hill, a business unit of The McGraw-Hill companies, Inc.
Copyright (c) 2006, 2003, 2000, 1998, 1995, 1992, 1989, 1986, 1983 by The McGraw-Hill companies, Inc.
Wiki User
∙ 11y agoThe reception of an impulse from a synapse to a dendrite.
The initiating step is when a strong enough summation of impulses reaches the axon hillock to open voltage gated sodium ion pores in the axon, which allow sodium ions in which open more sodium pores which continue that action down the axon.
Wiki User
∙ 15y agoAn action potential proper is generated by the opening of voltage-gated sodium channels located at a region of the neuron called the 'axon hillock'.
Wiki User
∙ 9y agoLocal polarization is the first step. Next the generation and propagation of an action potential. Lastly repolarization has to take place.
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Why is the action potential generated in neurons only?
may be there are specific arrangement of sodium and potassium ion channels in neurons which is not found in any other cell andthis arrangement is necessary for action potential generation but i am ot sure what kind of arrangement is needed for action potential generation and what kind is presentr in neurons and other cells .
What is the result of inhibitory neurotransmission on the postsynaptic membrane?
Hyperpolarization of the membrane. This inhibits action potential generation.
A virus causes damage to the sodium channels of the postsynaptic neuron such that they open very slowly in response to a neurotransmitter How does this modify the generation of an action potential?
The sodium influx necessary for depolarization will occur more slowly making the action potential difficult to generate.
When do you use relative refractory period?
The relative refractory period is the time during which the generation of an action potential is impossible no matter the strength of the stimulus
What substances plays a mojor role in generating the membrane potential of a neuron?
Well, for starters, membrane potential is a separation of charges across the membrane. So i think what you mean is "generating the action potential in a neuron". So in that case The substance that plays a major role in generating an action potential is Sodium (Na+). However, if you really mean membrane potential, there is only two substances associated with that and those are sodium (Na+) and potassium (K+).However, in truth, the generation of an action potential depends on the ligand and its receptor.
What is the earliest step in the generation of an action potential?
deporalization
Why is the action potential generated in neurons only?
may be there are specific arrangement of sodium and potassium ion channels in neurons which is not found in any other cell andthis arrangement is necessary for action potential generation but i am ot sure what kind of arrangement is needed for action potential generation and what kind is presentr in neurons and other cells .
What are the events that must occur to generate action potential?
Local polarization is the first step. Next the generation and propagation of an action potential. Lastly repolarization has to take place.
What ions enter the muscle cell during action potential generation?
sodium and potassium
The ions that enter the muscle cell during action potential generation are?
cacium ions
What is the result of inhibitory neurotransmission on the postsynaptic membrane?
Hyperpolarization of the membrane. This inhibits action potential generation.
Effects chlorine has on the generation and conduction of action potentials?
Influx of chloride ions into the neuron help to hyperpolarize the neuronal membrane, thus preventing the induction of an action potential. Therefore, chloride ions help to prevent generation of action potentials.
What is the period of time that elapses between the generation of an action potential and the start of muscle tension development in a muscle fiber?
latent period
A virus causes damage to the sodium channels of the postsynaptic neuron such that they open very slowly in response to a neurotransmitter How does this modify the generation of an action potential?
The sodium influx necessary for depolarization will occur more slowly making the action potential difficult to generate.
When do you use relative refractory period?
The relative refractory period is the time during which the generation of an action potential is impossible no matter the strength of the stimulus
WHAT are neurotransmitters are inhibitory?
neurotransmitters are called Inhibitory if the activation of the receptors causes hyper-polarisation and depresses action potential generation (slows down processes)
What substances plays a mojor role in generating the membrane potential of a neuron?
Well, for starters, membrane potential is a separation of charges across the membrane. So i think what you mean is "generating the action potential in a neuron". So in that case The substance that plays a major role in generating an action potential is Sodium (Na+). However, if you really mean membrane potential, there is only two substances associated with that and those are sodium (Na+) and potassium (K+).However, in truth, the generation of an action potential depends on the ligand and its receptor.
