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What is the advantage of having multiple receptor subtypes for a neurotransmitter?
Wiki User
∙ 11y ago
Multiple receptor subtypes allow for more "fine-tuned" neuromodulation of a given "signal" in a neural network. Each receptor subtype typically has a different binding affinity for the given neurotransmitter. Therefore, the neurotransmitter may bind more strongly or more weakly to one subtype over another.
This is most likely an effect of genetic variation, as the genes coding for the protein(s) present in the receptor slightly vary from subtype to subtype, yet still allow for binding by the neurotransmitter ligand.
Wiki User
∙ 11y ago
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