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A pyrogen is a bacterium that can produce fever as one of its clinical signs of infection. Sterile means there are no bacteria present on a surface, while pyrogen-free would indicate there are no bacteria present that will cause a fever.

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Q: What is the difference between sterile and pyrogen free?
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What is the difference between sterile water and bacterial static water?

sterile water is just free from microrganisms while pyrogen free water is specifically free from those orgainsms which cause fever.


What is the difference between demineralized water and battery water or distilled water..?

demineralised water is the water free from minerals but pyrogens will be present but in distilled water it is free from both mineral and pyrogen.


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By definition, aspetic means free of pathogenic microorganisms. Whereas Sterile means absence of all the microorganisms. While the difference is clear, both terms are sometimes used interchangably. For example, FDA has a guideline on processing the sterile drugs in the Aspetic environment. But this guideline does not draw a clear distinction between the two categories.


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Aseptic means being free (sterile) from contamination caused by harmful bacteria, viruses , etc. Septic means a wound that is festering.


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