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Esomeprazole (pronounced /iːsɵˈmɛprəzoʊl/) is a proton pump inhibitor (brand names Sompraz, Zoleri, Nexium, Lucen, Esopral; Axagon in Italy, Nexiam in Belgium and South Africa) developed and marketed by AstraZeneca which is used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and Zollinger-Ellison syndrome. Esomeprazole is the S-enantiomer of omeprazole (marketed as Losec/Prilosec), and AstraZeneca claims improved efficacy of this single enantiomer product over the racemic mixture of omeprazole. However, this greater efficacy has been disputed, with some[who?] claiming it offers no benefit from its older form.

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10y ago

Esomeprazole is a proton-pump inhibitor whose main purpose is to reduce the production of gastric acid on a long-term basis. The brand-name drug is known as Nexium.

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Q: What is the drug esomeprazole?
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Related questions

When was Esomeprazole created?

Esomeprazole was created in 2001.


Does esomeprazole cure chlamydia?

Esomeprazole is not an antibiotic, and it does not cure chlamydia.


List all PPI drug?

Omeprazole (Prilosec)Lanoprazole (Prevacid)Esomeprazole (Nexium)Pantoprazole (Protonix)Rabeprazole (Acifex)


Pharmacological deffarnece between omeprazole and esomeprazole?

Esomeprazole is an isomer of omeprazole.


Would lansoprazole and esomeprazole be in the same drug class?

Yes, they are considered to be in the same class. Both drugs are Proton Pump Inhibitors.


Is there aspirin in Nexium?

This drug contains absolutely no aspirin. Nexium is a proton pump inhibitor. The generic name for this drug is esomeprazole magnesium. It's effect is to reduce the amount of acid produced in your stomach and is a treatment for heartburn or indigestion. It has no relationship to aspirin.


Defferent esmprasozole and oprazole?

Yes, esomeprazole and omeprazole are different drugs. Esomeprazole is an active metabolite of "omeprazole" and is more active at the same dose. Both acts on "proton pump", reducing stomach acidity.


Does esomeprazole need to be mixed with sterile water for injection?

mixed with sterile water for injection


What is Molecular of Esomeprazole Magnesium Trihydrate?

the Molecular weight of Esomperazole Magnesium trihydrates is 767.17


Action of esomeprazole magnesium in body?

NEXIUM can cause serious side effects, including Diarrhea.


Is there a generic for nexium 20 mg?

Technically, there is no generic drug for Nexium (generic name is esomeprazole). However, esomeprazole is the isolated isomer (S-enantiomer) of omeprazole which you may know more as the over-the-counter drug Prilosec.Omeprazole and esomeprazole are both proton pump inhibitors, used to treat duodenal and gastric ulcers and gastro-esophageal reflux disease (GERD).When the patent was running out for omeprazole, AstraZeneca, the manufacturing company of omeprazole, developed the isolated form as a way to counter the loss of profit it would incur after the expiration of its patent. This practice is common among drug companies foreseeing the expiration of its major drugs.AstraZeneca marketed Nexium ("the purple pill") as a more potent and overall more effective drug than omeprazole. In actuality, although the S-enantiomer is more active than the R-enantiomer, the difference does not account for much. In general, the difference between a single active enantiomer and a mixture can be a difference in time of onset of action (sometimes 5 minutes) or it can be the strength of the dose (double the strength of the mixture). Compared to the relatively low cost of omeprazole, the more expensive cost of Nexium is not worth the differences between the two drugs. It may still be disputable however. Some people believe the active enantiomer does in fact provide better effectiveness than the racemic mixture.


What are the main drugs used as proton pump inhibitors?

There are five drugs in this class: esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), and rabeprazole (Aciphex).