Dr. Jonas Salk of La Jolla, California, developed the first polio vaccination. It was widely used in 1955 and for many years longer. The Salk Institute went on to do more important scientific developments.
Salk was the first to develop a polio vaccine. It was given by injection. It was composed of a killed virus. Another vaccine was developed by Sabin and was oral and a live attenuated virus.
FDR had polio, Mia Farrow, and Dinah Shore are a few survivors you may have heard about. A a child I had both because my family was so scared of this disease.
Dr. Jonas Salk. The angel physician. He did not take the patent of the vaccine.
The polio vaccine was developed in 1952 by Dr. Jonas Salk
Jonas Salk
The Pertussis vaccine was developed in 1921 but was not widely used till the 1930s.
There is no vaccine for leprosy. India and Brazil currently use the Bacillus Calmette Guerin (BCG) vaccine but that is for TB. The effectiveness of this approach is widely disputable and the search goes on.
There are several vaccines to prevent bacterial infections, but not nearly as many as there are for viral infections. One widely used today is the vaccine for bacterial pneumonia which has been very effective in reducing death from this infection in the elderly. Other frequently used vaccines for bacterial diseases include those for: meningitis, cholera, salmonella, anthrax, plague, Hib, and tuberculosis.
They first became widely available in 1993
Polio vaccine was one of the great public health developments of the 1950s.
The oral polio vaccine is a live virus that is mutated in order for it to be strong enough to induce an immune response but weak enough to not cause disease. This replication in the host of the live virus gave a better immune response and also allowed the vaccine strain to spread and inoculate people who did not directly (intentionally) received the disease. The problem is that rarely it could "back mutate" and actually produce polio disease. It is believed that when the oral polio vaccine was widely used in the US there were about 10 cases per year of vaccine induced polio (compared to thousands of cases per year of natural polio before the vaccine was developed). Some studies cast doubt on this number by carefully examining proposed cases and finding other causes in most of them. When the polio incidence became nearly zero it was decided that the advantaged of increased immunity and increased spread of the oral vaccine were not worth the vaccine induced cases and so the US, and most developed countries, switched to the injectable vaccine.
Battering rams became "old hat" when gunpowder became widely used in the West.
They first became widely available in 1993
Edward Jenner is most well known for performing the first cowpox vaccination that was then widely used. Others had done the same thing with cowpox, but Jenner's was the first to become widely known.
Bill Gates has donated $25 million to the International AIDS Vaccine Initiative, which is creating coalitions of research scientists, pharmaceutical companies and governments in developing countries to look for a safe, effective, widely accessible vaccine against AIDS.
A number of people were involved in the production of this bacterial vaccine. In the 1920' Dr. Sauer and Dr. Madson. Both of these were whole cell vaccines. Dr. Sato in Japan developed an acellular vaccine and it has been widely used in Japan since 1980. The effectiveness of these two last 3-6 years so boosters are needed.
Moonlighting