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the transfusion reaction doesn't occur the first time an Rh+ patient is exposed to Rh- blood because the Rh+ patients body hasn't created the antibodies needed to attack the Rh- blood that it comes in contact with. the second time the Rh+ patients body comes in contact with Rh- blood, it will have the antibodies necessary to fight against Rh- blood.

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Q: Why does a transfusion reaction not occur the first time a rh positive patient is exposed to rh negative blood?
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What happens in the blood of an RH negative who is exposed to RH positive blood?

severe reaction, because rh-ve person can't get rh+ve blood.


Why is it that an Rh-negative person does not have a transfusion reaction on the first exposure to Rh-positive blood but does have a reaction on the second exposure?

Because antibodies that cause the reaction are not naturally occurring. One has to be exposed to Rh in order to make antibodies to it. Its the same process as the reaction to a vaccine. The vaccine exposes you to an antigen and your body learns how to react to it in order to protect you from it. If you are exposed to the Rh factor, your body learns how to react to it, and so the next time you're exposed, the reaction is greater. The major blood groups are different. The antibodies occur naturally. A group O person typically has antibodies to blood from group A and group B donors. Whereas a group AB person doesn't have these antibodies. Also, there are lesser known antigen/antibody groups that can cause trouble. That's what makes my job in the Blood Bank more interesting.


Can Rh antibodies of Rh- be detected?

A person who is Rh negative may have antibodies if he or she has been exposed in the past to Rh positive blood. Rhogam will prevent this sensitization in a pregnant woman with negative blood carrying an Rh positive baby.


Is blood type O RH positive compatible with O positive?

Yes and no. When a blood type is described as being O+ or O-, there are actually two blood groups being described here: The letter (A, B, AB or O) refers to your blood type in the ABO blood group. The positive or negative sign refers to the Rh group; positive means that your blood cells have the D antigen, and negative means that your blood cells do not have the D antigen. In the ABO system, the possible antigens a person can have are A, and/or B. O simply denotes the absence of A and B. In this system, the body's immune system naturally produces antibodies against the antigens that it lacks; so, an O individual will have Anti-A and Anti-B, an A individual will only have Anti-B. In the Rh system, the immune system of an Rh-negative person generally does not produce Anti-D unless the person has been exposed to the antigen before through a previous transfusion or through pregnancy & childbirth. Once an Rh negative person is exposed to Rh-positive blood, there is an 85% chance that Anti-D will be produced. When an Rh-negative person with Anti-D in their blood is exposed to the D antigen on Rh-positive blood again, they may have a transfusion reaction. Their immune system will mount an attack against the cells, and the result could be anywhere from a fever and hives up to shock and death. Luckily, the chances of death from a transfusion now are very small, and if the doctors notice a transfusion reaction starting to occur, they can often stop the transfusion before the reaction gets worse. Many hospitals try to keep O-negative blood on hand for emergencies, but not every hospital is able to do this and O-positive may be the default blood for emergencies. The hospitals that do have O-negative blood on hand may only have limited resources; they may allow a patient to receive a limited amount of negative blood and if the patient is still bleeding, the medical director may allow the patient to be switched to positive blood. If an Rh-negative patient receives Rh-positive blood, they will give the patient an injection of Anti-D antibodies (such as WinRho or RhoGam) to attach to the D antigens, to reduce the chances of the patient's immune system noticing the D antigens and making it's own antibodies to it. WinRho is also given to pregnant women who are Rh-negative so that if their fetus is Rh-positive, their immune system doesn't start to attack the fetus. Anyhow, long story short: O positive isn't technically compatible and normally probably should not be given to O negative individuals, but in case of emergency, it is often better to give the O positive blood than it is to let the patient bleed out. However, O-negative people are normally compatible to give blood to O-positive people (unless there are other antibodies present in other blood group systems).


How many hours is the blood could be exposed from the blood bank before transfusion?

four hours


What does mechanosensitive mean?

Mechanosensitivity is the specific response done by certain organisms when exposed to mechanical activity. These responses can be positive or negative in nature, depending on the organism.


If you had a weak positive antibody test to hepatitis C but are not infected with it nor been exposed ever can you then get a negative result in another test or will it always be confused?

no


Is exposed an adjective?

It can be (an exposed negative, exposed secrets). The word exposed is a form of the verb to expose (to reveal).


In a enzyme reaction is exposed to an unfavorable pH what happens to the speed of the reaction?

catalyzed reaction


What would be the normal reaction to a dismal story?

A normal reaction to a dismal story might include feelings of sadness, empathy, or concern for the characters involved. It is natural to have an emotional response when being exposed to distressing or negative content.


If an enzyme reaction is exposed to an unfavorable pH what happens to the speed of the reaction?

It is reduced


Why do carbohydrates dissolve so easily in water?

Water is a polar molecule, meaning that the hydrogen end has a negative charge, while the oxygen end has a positive charge. When other polar molecules are exposed to these charges they split apart. In salt the sodium has a positive charge that is attracted to the hydrogen's negative charge, and a the chloride has a negative charge that is attracted to oxygen's positive charge.