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Unfortunately, it is not possible to run MS-DOS and Microsoft Windows applications on Windows Vista due to the differences in the system architecture. One option you might try is to download and use a Virtual Machine, which allows you to create an environment in which run older Windows or MS-DOS software.

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15y ago

you have run it in windows vista compatible mode right click on the file and then click on properties. you will find option run in compatible more.

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Q: 'the system file is not suitable for running MS-DOS and Microsoft Windows applications' Windows Vista error?
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