I would first check and see if you have fuel pressure, with a fuel gauge. should read 9 to 13 LBS. on gauge.
You can listen to see if the fuel pump is running by removing the gas cap and have someone to turn the key on while you listen at the gas cap. Pump should run. If not then check fuel pump relay and the fuel pump fuse. Those are under a black cover mounted on the passenger side of the fire wall. You must have fuel pressure before the injectors will pulse.
Check these things first. If you don't find the problem here then YOU will need to ask your question again.
Fuel pump bad, Fuel pump relay not working, Fuel pump fuse bad.
Your injectors stopped working because either they have failed and need to be replaced or else there is inadequate fuel pressure to open them.
it is probably a bad ignition module or computer
Need to replace the ignition module in the distributor, If you are sure the fuel pump is working.
Shouldn't-they are entirely electrical and pump is to maintain a certain pressure to the rail at all times. that pressure should be maintained if injectors are working or not . If it's not running, it's probably because it detects car not on. Most just prime but don't stay on unless engine starts.
Try a new Fuel filter, or a new fuel pressure regulator. Also check if the fuel pump is working, it could be electrical. Usually you can hear the pump buzzing if you're close to it.
running in the same problem. i come to conclusion its not EGR fuel pressure regulator or fuel pump. as the fuel pressure stays the same when this happens. it either has to be faulty injectors or ignition.
Just because you hear the pumps hum does not mean they are working. Also, where is the third pump? There should only be two, one in each tank. I am not aware of an F250 with a high pressure frame rail pump, how old is the truck? Have you pulled the fuel filter and checked for restriction? What happens when you pull the line off and turn the key on? Does fuel come out? When you say no fuel is getting to the engine, do you mean you have no fuel pressure, or the injectors aren't spraying anything? Could it be that fuel is getting to the fuel rail but the injectors are not firing? Could it be that you are getting some fuel pressure, but not enough fuel pressure? What if your fuel guage is wrong, and you have two empty fuel tanks? These are questions you need to answer to eliminate things down to your cause.
Fuel injectors need to be replaced every so often. If the fuel injectors are not working, they may be too old, and need to be replaced or put in properly.
If you are getting fuel the problem can be that your ingectors are not working check and see if your ingectors are working. When it runs for the 2 seconds it is burning off the starter fluid only, which means it probably isn't actually getting fuel into the chamber. So, I would agree and check to make sure your fuel injectors are firing. If they aren't you may have a bad fuel pump, which should be pushing about 40 psi (I think that is the right pressure). Depending on where you checked fuel flow, it may not have enough pressure to spray through injectors.
== ==
If the injector wires are not broken where the air cleaner sets on top of the Throttle body, then I would replace the ignition module that's in the distributor underneith the dist. cap.