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Genetics

2 Describe how point mutation and frameshift mutation affect the synthesis of proteins?

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2014-06-29 20:45:02
2014-06-29 20:45:02

A point mutation is a change in a single base pair in DNA. A change in a single nitrogenous base can change the entire structure of a protein because a change in a single amino acid can affect the shape of the protein.

A frameshift mutation is a mutation in which a single base is added or deleted from DNA. A single base is lost from a DNA strand which causes this new sequence with the deleted base, to be transcribed into mRNA. Then, the mRNA is out of position by one base. As a result, every codonafter the deleted base is different. This mutation causes nearly every amino acid in the protein after the deletion to be changed.

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