0
A defective P53 gene is likely to cause poor regulation of cell cycles. P53 is a protein that suppresses tumor production and is implicated as a factor in cancer development. It prevents genome mutation and damage. 50% of human tumors have mutated or deleted P53 genes.
Wiki User
∙ 12y ago
Wiki User
∙ 11y agoAdd your answer:
Earn +20 pts
What cancers does the p53 cancer gene cause?
P53 it is an anzyme that monitorize the DNA and protect them from demagis.It is founded that its defective in 60% of cancer cells
What role does p53 have in controlling cell division?
Cell division is regulated by the p53 gene and relates to cancer because Cancer is caused by uncontrolled cell divison
What is the P53 gene function?
p53 is a gene that codes for a protein (p53) that is an important tumor suppressor. Although the number of pathways and roles of p53 continue to expand it is, perhaps, most well known for slowing cell proliferation or inducing apoptosis if DNA damage or uncontrolled growth is detected.
What is the role of P53 in Cell Cycle Check Point?
The p53 Tumour suppressor gene is located on chromosome 17. As its name suggests, it has an anti-tumour activity. That involves the overseeing of the cell cycle. If either the cell or the DNA is impaired, p53 activates the production of specific chemicals (like p21 protein), which interferes with the cell cycle. Depending on the nature/extent of the damage, its either repaired, thus cell cycle is allowed to continue, or p53 initiate apoptosis (cell death). This mechanism would effectively stop the proliferation of infected (malignant) cells, however, p53 itself (or any of genes/chemicals p53 regulates) could be damaged/mutated. In the inherited condition, Li-Fraumeni syndrome, for example, only one functional copy of p53 gene is inherited (instead of two), which interferes with its normal function.
Who identified the p53 gene?
The p53 gene was identified in 1979 by Arnold Levine, David Lane, and William Old. It wasn't until 1989 that the gene was found to be a tumor suppressor.
What is p53 called?
"The Guardian Angel Gene"
What protein called p53 can keep cells from dividing To prevent cell division this process most likely stops?
respiration
What are point mutations?
Point mutations are a knock out of a single A.A. pair that shifts the whole code causing cancer or miss development of all the proteins behind it. Point mutations can be seen in K-Ras gene and the innactivation of the P53 to not stop the genetic mutation to arrect the cell cycle. The p53 is a tumor repressing gene.
Does The p53 gene codes for a protein that triggers uncontrolled cell division?
No, when it detects a mutation or damage to the DNA of a cell it codes for a protein that causes apoptosis to occur which is the controlled death of a cell. so it prevents uncontrolled cell division.
What is the medical term meaning Condition caused by defective genes?
genetic disorderOne is cancer that is related to a mutation or the deletion of the P53 gene. There are so many genetic disorders that listing them all would be impossible.
What will the result if the cell cycle is uncontrolledor if the cell continue to divide without stopping?
If the cell cannot stop dividing then a tumour will form. The tumour can be cancerous or benign. Uncontrolled cell division may be caused by substances called carcinogens (e.g. in cigarettes) which can switch the P53 gene off. This gene is responsible for controlling cell division.
What happens if gene p53 is suppressed?
When you fire it the bullet will make less noise.
