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Sulfonamide

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Q: An antimicroial that inhibits hepatic P450 microsomal enzymes?
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What is hepatic microsoal induction give examples?

Hepatic microsomal induction, you might mean, is as it is, induction of hepatic microsomal enzymes. These microsomal enzymes are found in the liver and are responsible for the metabolism of drugs that we take in. There are some drugs though, that can increase the activity of these enzymes. Some examples are: Dicoumarol Disulfiram Isoniazid Cimetidine Chloramphenicol Sulfonamides If these drugs are taken in along with another, the metabolism of the other drug will be decreased, resulting in an increased half life.


What is hepatic microsomal enzyme induction?

Hepatic microsomal enzyme induction or in other words the stimulation of the microsomal enzymes of the liver occur as a result of administration of certain drugs such as Phenobarbitone, Phenytoin or Carbamezapine. These drugs stimulate this enzyme system in the liver and accelerate the metabolism of other substances such as Coumarin anticoagulants that are administered to a person to prevent clotting tendency. In that case, the physician would consider increasing the dose of the Coumarin anticoagulants to achieve an optimum effect since the accelerated metabolism of these drugs will not produce the desired effect.


What is Microsomal oxidation?

Microsomal oxidation is the type of biological oxidation catalyzed by special cytochrome P-450 (CYP) enzyme group (superfamily) which takes place predominantly in hepatic microsomes, which are fragments of liver cells endoplasmatic membranes.


What does the liver do when detoxification?

The liver uses enzymes to alter chemicals and convert them fro fat-soluble forms to water-soluble forms which are more readily excreted through the urine and fecal matter.Follow the related link below (Liver Detox - Liver Cleanse) for more information.


What has the author Richard Milton Kardish written?

Richard Milton Kardish has written: 'Effect of pregnancy and role of progesterone metabolites in the regulation of the activity of enzymes bound to the hepatic endoplasmic reticulum' -- subject(s): Enzymes, Physiological effect, Drug metabolism, Progesterone


What is diffuse hepatic steatosis?

Also called "fatty liver," diffuse hepatic steatosis is a condition where fat is stored in the liver due to an accumulation of lipids like triglycerides. The main cause is diminished metabolism of fatty acids caused by the impairment of certain enzymes and receptors, insulin resistance, or the overconsumption of alcohol.


What veins drain the liver?

hepatic


Does ligation of hepatic artery cause hepatic infarction?

no


What is unusual about the hepatic portal vein?

The hepatic portal vein in frogs is unusual in that it is divided into two portals, the hepatic and the renal. In higher vertebrates, the hepatic portal system is the only one present.


What organ does hepatic refer to?

Hepatic refers to the liver.


What is A vein that sends blood to hepatic capillaries?

hepatic portal vein


What is attached to the hepatic duct?

Hepatic duct is attached with liver. The union of hepatic duct and cystic duct forms common bile duct.